HOMER3 and FAT1

Number of citations of the paper that reports this interaction (PubMedID 16979624)
14

Data Source:
HPRD (in vitro)

		HOMER3	FAT1
Description		homer scaffold protein 3	FAT atypical cadherin 1
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Dendrite	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Apical Plasma Membrane Lamellipodium Filopodium Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding G Protein-coupled Glutamate Receptor Binding Identical Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Protein Targeting G Protein-coupled Glutamate Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry	Lens Development In Camera-type Eye Epithelial Cell Morphogenesis Establishment Of Epithelial Cell Apical/basal Polarity Involved In Camera-type Eye Morphogenesis Actin Filament Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Establishment Or Maintenance Of Cell Polarity Cell-cell Signaling Anatomical Structure Morphogenesis Cell Migration Cell-cell Adhesion
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS			Alzheimer disease and age of onset ( 26830138) Carotid plaque burden ( 28282560) Chronotype ( 26955885) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Macular thickness ( 30535121) Major depressive disorder ( 29317602) Medication use (calcium channel blockers) ( 31015401) Morning vs. evening chronotype ( 26955885) Obesity ( 21552555) PR interval ( 30046033 32439900) Triglyceride levels in HIV infection ( 33109212) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		92 interacting genes: ABI1 ABI2 ABI3 APP ARL13B C1orf116 C4orf17 CCDC120 CCDC141 CCDC187 CDC37 CDK18 CEBPB CWF19L2 DVL3 DYNLL1 DYNLL2 EAF1 EFHC1 EIF3D FAM161B FAM90A1 FAT1 FBXO28 FMR1 FRYL FXR1 FXR2 GAS8 GDF15 GGN GRM5 HOMER1 HOXB5 INCA1 ITPR1 KANK2 KANK4 KDM1A KRTAP19-7 LHX2 LNX1 LRRC7 LSM14B MDM1 MEOX1 MFAP1 MIA3 MOS MSS51 NEBL NTAQ1 OTX2 PALLD PAX6 PAX7 PKN1 PLAAT5 POLI POM121 PPP1R18 PPP1R32 PRCC PRR35 PSMA1 PSMA2 PSMC5 PSORS1C2 RBM14 RBM22 RUNX1T1 RYR1 SAXO1 SCNM1 SDCBP SHANK3 SLAIN1 SMR3B SNRPF SRPK2 TBC1D22B TOX2 TRPC1 TSC1 USP2 WBP2 WIPF1 ZBTB4 ZNF19 ZNF35 ZNF414 ZNF655	12 interacting genes: CLK1 ENAH HOMER1 HOMER3 IGLL1 MT-ND1 NOXA1 SORBS2 TRAF4 TRIM14 UBC VASP
Entrez ID		9454	2195
HPRD ID		07270	02986
Ensembl ID		ENSG00000051128	ENSG00000083857
Uniprot IDs		Q9NSC5	Q14517
PDB IDs		2P8V 3CVF
Enriched GO Terms of Interacting Partners?
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