MTA2 and SATB2

Number of citations of the paper that reports this interaction (PubMedID 18333962)
57

Data Source:
BioGRID (pull down)

		MTA2	SATB2
Description		metastasis associated 1 family member 2	SATB homeobox 2
Image		No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Nucleoplasm Transcription Regulator Complex Membrane NuRD Complex Protein-containing Complex	Histone Deacetylase Complex Chromatin Nucleoplasm Transcription Regulator Complex Nuclear Matrix
	Molecular Function	Transcription Coactivator Activity Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Zinc Ion Binding Nucleosomal DNA Binding Histone Deacetylase Binding Sequence-specific DNA Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Chromatin Assembly Or Disassembly Chromatin Remodeling Regulation Of Fibroblast Migration Histone Deacetylation Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Osteoblast Development Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Embryonic Pattern Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Cartilage Development Roof Of Mouth Development Cellular Response To Organic Substance
Pathways		HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Potential therapeutics for SARS	SUMOylation of chromatin organization proteins RUNX2 regulates osteoblast differentiation
Drugs
Diseases
GWAS		Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Autism spectrum disorder or schizophrenia ( 28540026) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Brain cytoarchitecture ( 20308991) Cerebrospinal fluid immune biomarker levels ( 32066700) Chin dimples ( 27182965) Colorectal cancer or advanced adenoma ( 30510241) Cortical volume ( 32963231) FEV1 ( 30804560) Heel bone mineral density ( 30598549) Height ( 31562340) Insomnia ( 23728906) Loneliness (multivariate analysis) ( 27629369) Lung function (FVC) ( 30804560) Menarche (age at onset) ( 27182965 29773799 25231870) Rheumatoid arthritis ( 30891314) Schizophrenia ( 28991256 25056061 29483656 30285260) Serum alkaline phosphatase levels ( 33547301) Sun-seeking behavior ( 32920024) Type 2 diabetes ( 25760438) Ulcerative colitis ( 20228799) Waist circumference ( 23966867)
Interacting Genes		23 interacting genes: APPL1 APPL2 BCL11B ERCC6 ESR1 FKBP3 H3-4 HNRNPD MBD3 MBD3L2 MED30 NACC2 RBBP4 RBBP7 SATB1 SATB2 SPEN SUMO2 TP53 TSC22D3 UBE3C USP11 YY1	7 interacting genes: ABI2 ADAM23 HDAC1 MTA2 PIAS1 POLR2J3 RAB3IL1
Entrez ID		9219	23314
HPRD ID		07233	12178
Ensembl ID		ENSG00000149480	ENSG00000119042
Uniprot IDs		A0A024R534 O94776	A0A024R3U6 B3KPQ9 Q59FT3 Q9UPW6
PDB IDs			1WI3 1WIZ 2CSF
Enriched GO Terms of Interacting Partners?
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