MTA2 and FKBP3

Number of citations of the paper that reports this interaction (PubMedID 12920132)
55

Data Source:
BioGRID (pull down)

		MTA2	FKBP3
Description		metastasis associated 1 family member 2	FKBP prolyl isomerase 3
Image		No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Nucleoplasm Transcription Regulator Complex Membrane NuRD Complex Protein-containing Complex	Nucleus
	Molecular Function	Transcription Coactivator Activity Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Zinc Ion Binding Nucleosomal DNA Binding Histone Deacetylase Binding Sequence-specific DNA Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Signaling Receptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Chromatin Assembly Or Disassembly Chromatin Remodeling Regulation Of Fibroblast Migration Histone Deacetylation Positive Regulation Of Transcription By RNA Polymerase II	Protein Peptidyl-prolyl Isomerization
Pathways		HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Potential therapeutics for SARS
Drugs
Diseases
GWAS		Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Hypertensive renal disease ( 34067580)
Interacting Genes		23 interacting genes: APPL1 APPL2 BCL11B ERCC6 ESR1 FKBP3 H3-4 HNRNPD MBD3 MBD3L2 MED30 NACC2 RBBP4 RBBP7 SATB1 SATB2 SPEN SUMO2 TP53 TSC22D3 UBE3C USP11 YY1	16 interacting genes: BARD1 CALM1 CDC42 CSNK2A1 CSNK2A2 CSNK2B ERBB2 FBXO25 HDAC1 HDAC2 MTA2 NEDD4 NEDD4L SMURF1 SRPK1 YY1
Entrez ID		9219	2287
HPRD ID		07233	01743
Ensembl ID		ENSG00000149480	ENSG00000100442
Uniprot IDs		A0A024R534 O94776	Q00688
PDB IDs			1PBK 2KFV 2MPH 5D75 5GPG
Enriched GO Terms of Interacting Partners?
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