DERL3 and RTP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DERL3	RTP4
Description		derlin 3	receptor transporter protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase ERAD-L Complex Integral Component Of Endoplasmic Reticulum Membrane	Cytoplasm Integral Component Of Membrane
	Molecular Function	Signal Recognition Particle Binding Protein Binding Protein-containing Complex Binding Misfolded Protein Binding Ubiquitin-specific Protease Binding	Protein Binding Olfactory Receptor Binding
	Biological Process	Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Protein Targeting To Membrane Protein Insertion Into Membrane Defense Response To Virus
Pathways		ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis	Olfactory Signaling Pathway
Drugs
Diseases
GWAS		Ejection fraction ( 29403010) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Left ventricular internal dimension in systole ( 29403010) PR interval ( 32439900) S-phenylmercapturic acid levels in smokers ( 26959369)	Impulsivity (attentional) ( 30718321)
Interacting Genes		19 interacting genes: EHHADH GAD2 GNLY GPR101 IL27RA MELTF NDRG4 PSCA RTP4 SDCBP SERPINA1 SLC13A4 STATH SYT16 TEX29 TMEM179B TMEM31 TMEM92 ULBP2	5 interacting genes: DERL3 OPRM1 REEP4 TAS2R10 TRARG1
Entrez ID		91319	64108
HPRD ID		13139	17136
Ensembl ID		ENSG00000099958	ENSG00000136514
Uniprot IDs		Q96Q80	Q96DX8
PDB IDs
Enriched GO Terms of Interacting Partners?
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