DERL3 and TEX29

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DERL3	TEX29
Description		derlin 3	testis expressed 29
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase ERAD-L Complex Integral Component Of Endoplasmic Reticulum Membrane	Integral Component Of Membrane
	Molecular Function	Signal Recognition Particle Binding Protein Binding Protein-containing Complex Binding Misfolded Protein Binding Ubiquitin-specific Protease Binding	Protein Binding
	Biological Process	Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis
Drugs
Diseases
GWAS		Ejection fraction ( 29403010) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Left ventricular internal dimension in systole ( 29403010) PR interval ( 32439900) S-phenylmercapturic acid levels in smokers ( 26959369)	Adult body size ( 32376654) Chronotype ( 30696823) Initial pursuit acceleration ( 29064472) Lead levels ( 26025379) Menarche (age at onset) ( 27182965 25231870) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		19 interacting genes: EHHADH GAD2 GNLY GPR101 IL27RA MELTF NDRG4 PSCA RTP4 SDCBP SERPINA1 SLC13A4 STATH SYT16 TEX29 TMEM179B TMEM31 TMEM92 ULBP2	24 interacting genes: APOD C14orf180 CLEC2A CLEC7A CLRN2 CMTM7 DERL3 FAM3C FBXO7 GJB2 GPHB5 MAL RHAG RUSF1 SLC35B2 SMCO4 TMBIM6 TMEM11 TMEM140 TMEM147 TMEM19 TMEM190 TMEM86B ZFPL1
Entrez ID		91319	121793
HPRD ID		13139	14603
Ensembl ID		ENSG00000099958	ENSG00000153495
Uniprot IDs		Q96Q80	Q8N6K0
PDB IDs
Enriched GO Terms of Interacting Partners?
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