TM4SF5 and AMIGO1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TM4SF5	AMIGO1
Description		transmembrane 4 L six family member 5	adhesion molecule with Ig like domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Integral Component Of Membrane Dendrite Neuronal Cell Body Membrane Perikaryon Pericellular Basket
	Molecular Function	Protein Binding Arginine Binding	Protein Binding Potassium Channel Regulator Activity
	Biological Process	Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Axonogenesis Axonal Fasciculation Brain Development Positive Regulation Of Neuron Projection Development Myelination Positive Regulation Of Axonogenesis Positive Regulation Of Synapse Assembly Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Voltage-gated Potassium Channel Activity Cellular Response To L-glutamate
Pathways
Drugs
Diseases
GWAS		Initial alcohol sensitivity ( 30276832) Metabolite levels ( 22916037) Triglyceride levels ( 32203549) Triglycerides ( 25961943)	Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) LDL cholesterol levels ( 32203549) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189)
Interacting Genes		1 interacting genes: AMIGO1	35 interacting genes: ADIPOQ AMIGO2 AMIGO3 ANKRD46 ASGR1 BNIP3 C3orf52 CLDN11 CXCL9 EDDM3B GJB2 HHATL IGFBP5 LMO3 MALL NINJ2 NKG7 PGA4 PGAP2 PLPP6 PROM2 PTTG1IP RPRM SELENOK SLC38A1 SLC38A7 SLC41A1 STX8 TM4SF5 TMEM50B TMEM60 TMEM79 TNMD TSPO UPK2
Entrez ID		9032	57463
HPRD ID		06877	11129
Ensembl ID		ENSG00000142484	ENSG00000181754
Uniprot IDs		O14894	Q86WK6
PDB IDs
Enriched GO Terms of Interacting Partners?
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