PEA15 and PDE4DIP

Number of citations of the paper that reports this interaction (PubMedID 24710276)
4

Data Source:
BioGRID (two hybrid)

		PEA15	PDE4DIP
Description		proliferation and apoptosis adaptor protein 15	phosphodiesterase 4D interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Microtubule Associated Complex	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril
	Molecular Function	Protein Binding	Protein Binding Enzyme Binding Molecular Adaptor Activity
	Biological Process	MAPK Cascade Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Cellular Protein-containing Complex Assembly Regulation Of Golgi Organization
Pathways		RAF-independent MAPK1/3 activation RAF/MAP kinase cascade
Drugs
Diseases
GWAS			Capecitabine sensitivity ( 22864933) Cutaneous mastocytosis ( 32752121) Macrovascular complications in type 2 diabetes ( 33430853) Mastocytosis ( 32752121)
Interacting Genes		40 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RPSA RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13	95 interacting genes: ADH1B AEN AKTIP ANKRD11 ARNT2 BYSL C1orf109 CCDC146 CCDC198 CDC5L CDKN1A CHCHD3 CHD1L CLIP4 CWF19L2 EGR2 EIF4E2 FAM161A FAM50B FAM74A4 FCHSD2 FES FHL1 GADD45G GBE1 GFI1B GNRHR2 GOLGA5 GOLGA8EP GOLGA8F HAUS1 HOXB5 HOXC8 ITSN2 KDM1A KLC3 KLC4 KRAS KRT1 KRT18 KRT31 LAMTOR3 LENG1 LIN37 LMO4 MAPRE3 MIF4GD MTUS2 MYBPC2 MYOM1 NAA10 NEFL NEK2 OSGEP PDE4D PEA15 PFDN1 PIAS4 PPP1R18 PRNP PRPF31 PYGM RBM8A RTP5 SCNM1 SDCBP SH2D4A SHFL SMN1 SNCA TEAD4 TFIP11 THRB TK1 TMOD4 TNIK TRAF4 TULP3 UTP14C VAC14 ZBTB24 ZBTB38 ZBTB4 ZDHHC17 ZFYVE21 ZKSCAN3 ZNF124 ZNF408 ZNF410 ZNF414 ZNF512B ZNF581 ZNF587 ZNF696 ZSCAN26
Entrez ID		8682	9659
HPRD ID		04579	10482
Ensembl ID		ENSG00000162734	ENSG00000178104
Uniprot IDs		B1AKZ4 B1AKZ5 Q15121 Q96FS5	A0A075B749 A0A087WYE4 Q5VU43
PDB IDs		4IZ5 4IZA 6P6B 6P6C
Enriched GO Terms of Interacting Partners?
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