PDE4DIP and LIN37

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PDE4DIP	LIN37
Description		phosphodiesterase 4D interacting protein	lin-37 DREAM MuvB core complex component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril	Nucleoplasm Transcription Repressor Complex Myb Complex
	Molecular Function	Protein Binding Enzyme Binding Molecular Adaptor Activity	Protein Binding
	Biological Process	Cellular Protein-containing Complex Assembly Regulation Of Golgi Organization	Negative Regulation Of Transcription By RNA Polymerase II
Pathways			Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS		Capecitabine sensitivity ( 22864933) Cutaneous mastocytosis ( 32752121) Macrovascular complications in type 2 diabetes ( 33430853) Mastocytosis ( 32752121)	Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278)
Interacting Genes		95 interacting genes: ADH1B AEN AKTIP ANKRD11 ARNT2 BYSL C1orf109 CCDC146 CCDC198 CDC5L CDKN1A CHCHD3 CHD1L CLIP4 CWF19L2 EGR2 EIF4E2 FAM161A FAM50B FAM74A4 FCHSD2 FES FHL1 GADD45G GBE1 GFI1B GNRHR2 GOLGA5 GOLGA8EP GOLGA8F HAUS1 HOXB5 HOXC8 ITSN2 KDM1A KLC3 KLC4 KRAS KRT1 KRT18 KRT31 LAMTOR3 LENG1 LIN37 LMO4 MAPRE3 MIF4GD MTUS2 MYBPC2 MYOM1 NAA10 NEFL NEK2 OSGEP PDE4D PEA15 PFDN1 PIAS4 PPP1R18 PRNP PRPF31 PYGM RBM8A RTP5 SCNM1 SDCBP SH2D4A SHFL SMN1 SNCA TEAD4 TFIP11 THRB TK1 TMOD4 TNIK TRAF4 TULP3 UTP14C VAC14 ZBTB24 ZBTB38 ZBTB4 ZDHHC17 ZFYVE21 ZKSCAN3 ZNF124 ZNF408 ZNF410 ZNF414 ZNF512B ZNF581 ZNF587 ZNF696 ZSCAN26	17 interacting genes: CCNDBP1 CDR2 CEP70 KIFC3 KRT31 KRT40 LZTS2 MAGEA6 MEOX2 PDE4DIP PNMA1 PSTPIP1 TEX11 TFIP11 TRAF1 TRIM54 ZNF76
Entrez ID		9659	55957
HPRD ID		10482	16872
Ensembl ID		ENSG00000178104	ENSG00000267796
Uniprot IDs		A0A075B749 A0A087WYE4 Q5VU43	Q96GY3
PDB IDs
Enriched GO Terms of Interacting Partners?
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