PDE4DIP and HOXB5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PDE4DIP	HOXB5
Description		phosphodiesterase 4D interacting protein	homeobox B5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril	Chromatin Fibrillar Center Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Enzyme Binding Molecular Adaptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cellular Protein-containing Complex Assembly Regulation Of Golgi Organization	Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Endothelial Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis
Pathways
Drugs
Diseases
GWAS		Capecitabine sensitivity ( 22864933) Cutaneous mastocytosis ( 32752121) Macrovascular complications in type 2 diabetes ( 33430853) Mastocytosis ( 32752121)	Diverticular disease ( 30177863) Obesity ( 22484627)
Interacting Genes		95 interacting genes: ADH1B AEN AKTIP ANKRD11 ARNT2 BYSL C1orf109 CCDC146 CCDC198 CDC5L CDKN1A CHCHD3 CHD1L CLIP4 CWF19L2 EGR2 EIF4E2 FAM161A FAM50B FAM74A4 FCHSD2 FES FHL1 GADD45G GBE1 GFI1B GNRHR2 GOLGA5 GOLGA8EP GOLGA8F HAUS1 HOXB5 HOXC8 ITSN2 KDM1A KLC3 KLC4 KRAS KRT1 KRT18 KRT31 LAMTOR3 LENG1 LIN37 LMO4 MAPRE3 MIF4GD MTUS2 MYBPC2 MYOM1 NAA10 NEFL NEK2 OSGEP PDE4D PEA15 PFDN1 PIAS4 PPP1R18 PRNP PRPF31 PYGM RBM8A RTP5 SCNM1 SDCBP SH2D4A SHFL SMN1 SNCA TEAD4 TFIP11 THRB TK1 TMOD4 TNIK TRAF4 TULP3 UTP14C VAC14 ZBTB24 ZBTB38 ZBTB4 ZDHHC17 ZFYVE21 ZKSCAN3 ZNF124 ZNF408 ZNF410 ZNF414 ZNF512B ZNF581 ZNF587 ZNF696 ZSCAN26	62 interacting genes: ASB6 AXIN2 CADPS CALCOCO2 CARD9 CCDC136 CCDC88B CEP70 CNFN CSNK2B CTBP1 CTBP2 CYSRT1 GOLGA2 GOLGA6A GOLGA6L9 HAP1 HOMER3 HOOK2 HSF2BP KIFAP3 KRT31 KRT34 KRTAP1-1 KRTAP10-6 KRTAP10-8 KRTAP6-3 LDOC1 MAGEA11 MEOX2 MID2 MTUS2 NFKBID OIP5 PBX1 PBX2 PBX4 PDE4DIP PHF19 PLXND1 PRDM14 RCHY1 TBC1D26 TEKT4 TEX11 TLE5 TRAF1 TRAF2 TRAF4 TRIB3 TRIM23 TRIM27 TRIM54 USH1G VPS52 ZC4H2 ZMYND12 ZNF286A ZNF552 ZNF655 ZNF774 ZRANB1
Entrez ID		9659	3215
HPRD ID		10482	00848
Ensembl ID		ENSG00000178104	ENSG00000120075
Uniprot IDs		A0A075B749 A0A087WYE4 Q5VU43	P09067
PDB IDs
Enriched GO Terms of Interacting Partners?
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