LCE3D and TENM4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LCE3D	TENM4
Description		late cornified envelope 3D	teneurin transmembrane protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	Protein Binding	Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Keratinization	Gastrulation With Mouth Forming Second Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Regulation Of Myelination Positive Regulation Of Myelination Central Nervous System Myelin Formation Neuron Development Positive Regulation Of Oligodendrocyte Differentiation Cardiac Muscle Cell Proliferation Cardiac Cell Fate Specification Positive Regulation Of Gastrulation
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Psoriasis ( 25854761 20953190 23143594 19169255)	Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Hair greying ( 26926045) Lactate dehydrogenase levels ( 29403010) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lung cancer in never smokers ( 28604730) Night sleep phenotypes ( 27126917) Right lateral prefrontal cortical growth ( 29682794) Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483) Tourette syndrome ( 30818990)
Interacting Genes		55 interacting genes: ADAMTSL4 ALPP CCN3 CHIC2 CYSRT1 EFEMP1 EFEMP2 FBLN2 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-12 KRTAP4-2 KRTAP4-5 KRTAP5-3 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE2B LCE2C MDFI NBPF19 NOTCH2NLA PCSK5 RGS17 RGS20 SDC3 SPRY1 SPRY3 SRPK1 SRPK2 TENM4 TGFB1 TRIM42 TSPAN4 VWC2	11 interacting genes: DOCK2 GAB2 HOXB9 LCE3D LGALS4 PLSCR4 RSF1 SHFL TMEM126B ZNF587 ZNF696
Entrez ID		84648	26011
HPRD ID		17263	19400
Ensembl ID		ENSG00000163202	ENSG00000149256
Uniprot IDs		Q9BYE3	Q6N022
PDB IDs
Enriched GO Terms of Interacting Partners?
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