SYVN1 and ATL1

Number of citations of the paper that reports this interaction (PubMedID 32916628)
1

Data Source:
BioGRID (enzymatic study)

		SYVN1	ATL1
Description		synoviolin 1	atlastin GTPase 1
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GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase Complex Hrd1p Ubiquitin Ligase ERAD-L Complex Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Smooth Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Derlin-1 Retrotranslocation Complex Endoplasmic Reticulum Quality Control Compartment	Golgi Cis Cisterna Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane Axon Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Membrane
	Molecular Function	Protein Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding ATPase Binding Ubiquitin Protein Ligase Activity Ubiquitin-specific Protease Binding	GTPase Activity Protein Binding GTP Binding Identical Protein Binding
	Biological Process	Immature B Cell Differentiation Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol ERAD Pathway Protein Stabilization Protein K48-linked Ubiquitination Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Endoplasmic Reticulum Mannose Trimming	Endoplasmic Reticulum Organization Axonogenesis Protein Homooligomerization Endoplasmic Reticulum Tubular Network Membrane Organization
Pathways		XBP1(S) activates chaperone genes Hedgehog ligand biogenesis Hh mutants are degraded by ERAD ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Crohn's disease ( 32581322)	Cognitive performance ( 20125193) Dupuytren's disease ( 28886342) Periodontal disease-related phenotype (Socransky) ( 24347629)
Interacting Genes		14 interacting genes: APP ATL1 ATN1 CLU ERN1 GPR37 TP53 UBE2D2 UBE2D3 UBE2G1 UBE2U UBE2Z USP15 USP7	4 interacting genes: DNAAF2 KLHDC2 NIN SYVN1
Entrez ID		84447	51062
HPRD ID		07618	05918
Ensembl ID		ENSG00000162298	ENSG00000198513
Uniprot IDs		Q86TM6	A0A0S2Z5A2 A0A0S2Z5B0 Q53F53 Q8WXF7
PDB IDs		6A3Z	3Q5D 3Q5E 3QNU 3QOF 4IDN 4IDO 4IDP 4IDQ 6B9D 6B9E 6B9F 6B9G
Enriched GO Terms of Interacting Partners?
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