ITM2C and UPK2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ITM2C	UPK2
Description		integral membrane protein 2C	uroplakin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Integral Component Of Plasma Membrane Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Amyloid-beta Binding Protein Binding ATP Binding	Protein Binding
	Biological Process	Negative Regulation Of Neuron Projection Development Neuron Differentiation Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Multicellular Organism Development Epithelial Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Asthma ( 31959851)
Interacting Genes		13 interacting genes: AGAP1 BACE1 CCL4L2 CXCL9 FNDC9 FURIN MTNR1B OLFM4 PRODH RNF7 SLC22A2 STT3A UPK2	33 interacting genes: ADGRG3 AMIGO1 ASGR2 ATP6AP2 BSCL2 BTNL9 C3orf52 CD74 CLDN7 CLEC17A CLEC7A FCGR1A FCGR2A FCGRT FNDC9 GPA33 HPN ITM2C KASH5 KIR2DL3 KIR3DL3 LIME1 PLP1 RNF170 SLC22A23 SMAGP STOML3 TMEM106C TMPRSS2 TNFSF11 TNFSF14 UPK1A ZNRF4
Entrez ID		81618	7379
HPRD ID		17167	10295
Ensembl ID		ENSG00000135916	ENSG00000110375
Uniprot IDs		B8ZZM6 Q9NQX7	O00526
PDB IDs
Enriched GO Terms of Interacting Partners?
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