ZNF212 and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
46

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		ZNF212	SUV39H2
Description		zinc finger protein 212	SUV39H2 histone lysine methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding	Transcription Cis-regulatory Region Binding Protein Binding Zinc Ion Binding Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways		Generic Transcription Pathway	PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		31 interacting genes: - ATF3 ATF4 BYSL CREB3L2 CSK DPF2 DUSP6 FAM90A1 FHL2 FXR1 GAS8 GNL1 GYS1 HBP1 KANK2 MLH1 NFKBIA NKX2-3 PPARGC1B PRKAA2 PTP4A1 RND1 SAP30BP SF3A3 SUV39H2 ZNF3 ZNF331 ZNF408 ZNF783 ZZZ3	41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		7988	79723
HPRD ID		03859	07580
Ensembl ID		ENSG00000170260	ENSG00000152455
Uniprot IDs		A0A090N8N3 B3KQE6 Q9UDV6	Q9H5I1
PDB IDs			2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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