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SUV39H2

Description SUV39H2 histone lysine methyltransferase
Image
GO Annotations Cellular Component
  • Chromosome, Centromeric Region
  • Chromatin
  • Nucleus
  • Nucleoplasm
Molecular Function
  • Transcription Cis-regulatory Region Binding
  • Protein Binding
  • Zinc Ion Binding
  • Histone-lysine N-methyltransferase Activity
  • Histone Methyltransferase Activity (H3-K9 Specific)
  • S-adenosyl-L-methionine Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Chromatin Assembly Or Disassembly
  • Chromatin Remodeling
  • Cell Cycle
  • Cell Differentiation
  • Histone Lysine Methylation
  • Histone H3-K9 Dimethylation
  • Histone H3-K9 Trimethylation
  • Negative Regulation Of Circadian Rhythm
  • Negative Regulation Of Transcription, DNA-templated
  • Rhythmic Process
  • Cellular Response To Hypoxia
Pathways
  • PKMTs methylate histone lysines
Drugs
Diseases
GWAS
  • Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes 41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID 79723
HPRD ID 07580
Ensembl ID ENSG00000152455
Uniprot IDs Q9H5I1
PDB IDs 2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025