Description |
BAALC binder of MAP3K1 and KLF4 |
mitogen-activated protein kinase kinase kinase 1 |
Image |
No pdb structure |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Breast cancer and/or colorectal cancer ( 29698419)
- Late-onset Alzheimer's disease ( 27770636)
- Triglyceride levels x loop diuretics use interaction ( 31806883)
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- Alanine aminotransferase levels ( 33547301 33339817)
- Alanine transaminase levels ( 29403010)
- Blond vs. brown/black hair color ( 30531825)
- Body shape index ( 34021172)
- Brain morphology (MOSTest) ( 32665545)
- Breast cancer ( 29059683 17529967 23535729 31757997 20453838 19330030)
- Breast cancer (early onset) ( 24493630)
- Brown vs. black hair color ( 30531825)
- Coronary artery disease ( 29212778)
- Cortical surface area (MOSTest) ( 32665545)
- Fasting blood insulin ( 25631608)
- Fasting glucose in pregnancy (gestational week 14-16) ( 30324795)
- Fasting insulin ( 33402679)
- Fasting insulin (dietary factor interaction) ( 24204828)
- Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828)
- Initial pursuit acceleration ( 29064472)
- Lung function (FEV1) ( 30061609)
- Refractive error ( 32231278)
- Serum alkaline phosphatase levels ( 33547301)
- Sexual dimorphism in anthropometric traits ( 23754948)
- Subcortical volume (MOSTest) ( 32665545)
- Triglyceride levels ( 28334899 32902719)
- Triglycerides ( 24097068 20686565)
- Type 2 diabetes ( 23209189)
- Urate levels (BMI interaction) ( 25811787)
- Waist circumference ( 23966867)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in active individuals ( 28448500)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
- Waist circumference adjusted for body mass index ( 25673412 28448500)
- Waist-hip index ( 34021172)
- Waist-hip ratio ( 25673412)
- Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
- Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
- Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
- Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
- Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
- White matter hyperintensity volume ( 33293549)
- White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
- White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
- Youthful appearance (self-reported) ( 32339537)
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Interacting Genes |
13 interacting genes:
AGTR1
AP1G1
ATP1B3
ATXN1
CHD1L
CHEK2
CINP
MAP3K1
MDFI
NAA10
NAA11
OSBPL1A
RNF2
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97 interacting genes:
ACTN1
APEX2
APPL1
ARHGAP4
ASCC2
ATXN3
BAALC
BAP1
BRCA1
CARD14
CCDC69
CD74
CEP85
CHRM5
CHUK
COPS6
CRELD1
CRTC1
CUEDC1
DCUN1D1
DCUN1D2
DENND6B
DNAJB2
DNAJB6
DTX1
EPHA1
EPN1
FAF2
FAM184A
FKBP6
GGA2
GRIPAP1
GSK3B
HBS1L
HGS
HIP1
IKBKB
ILRUN
IMPACT
KRT36
MAP2K4
MAP2K7
MAPK1
MAPK9
MBP
MINDY3
NEK10
NFKBIA
NOTCH1
NPLOC4
NR4A1
ODF2
PAK1
PLEKHB2
PSMD4
RAB3IL1
RABEP2
RAD18
RAD23A
RAD51AP1
RAF1
RBCK1
RIPK1
RNF114
RNF126
RNF141
SPART
STAM
STAM2
TAB1
TNIP1
TOM1
TOM1L2
TP53
TRAF2
UBAC1
UBAP1
UBASH3B
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2G1
UBE2I
UBE2K
UBE2L6
UBE2V1
UBE2W
UBQLN1
UBXN7
UCHL5
UFD1
USP28
YWHAE
ZFAND3
ZFAND5
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Entrez ID |
79870 |
4214 |
HPRD ID |
09422 |
19599 |
Ensembl ID |
ENSG00000164929
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ENSG00000095015
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Uniprot IDs |
Q8WXS3
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Q13233
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PDB IDs |
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6WHB
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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