BAALC and OSBPL1A

Number of citations of the paper that reports this interaction (PubMedID 26050649)
15

Data Source:
BioGRID (two hybrid)

		BAALC	OSBPL1A
Description		BAALC binder of MAP3K1 and KLF4	oxysterol binding protein like 1A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Neuron Projection Membrane Raft	Endosome Late Endosome Cytosol Membrane Intracellular Membrane-bounded Organelle Organelle Membrane Contact Site Extracellular Exosome
	Molecular Function		Protein Binding Phospholipid Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding
	Biological Process		Bile Acid Biosynthetic Process Cholesterol Metabolic Process Sterol Transport Vesicle-mediated Transport
Pathways			Synthesis of bile acids and bile salts MHC class II antigen presentation
Drugs
Diseases
GWAS		Breast cancer and/or colorectal cancer ( 29698419) Late-onset Alzheimer's disease ( 27770636) Triglyceride levels x loop diuretics use interaction ( 31806883)	Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Neutrophil count ( 32888494) Osteoporosis-related phenotypes ( 20548944) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 25483131) White blood cell count ( 32888494)
Interacting Genes		13 interacting genes: AGTR1 AP1G1 ATP1B3 ATXN1 CHD1L CHEK2 CINP MAP3K1 MDFI NAA10 NAA11 OSBPL1A RNF2	5 interacting genes: BAALC MEOX2 PEA15 TIAM1 TSC22D2
Entrez ID		79870	114876
HPRD ID		09422	09472
Ensembl ID		ENSG00000164929	ENSG00000141447
Uniprot IDs		Q8WXS3	B0YJ56 B3KU11 Q6GSK5 Q9BXW6
PDB IDs			5ZM5 5ZM6 5ZM7 6IYB 6TQS
Enriched GO Terms of Interacting Partners?
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