AAGAB and HEATR1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		AAGAB	HEATR1
Description		alpha and gamma adaptin binding protein	HEAT repeat containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Nuclear Speck	Fibrillar Center Nucleoplasm Nucleolus Mitochondrion Membrane 90S Preribosome Small-subunit Processome T-UTP Complex
	Molecular Function	Protein Binding	RNA Binding Protein Binding SnoRNA Binding
	Biological Process	Protein Transport	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Positive Regulation Of Transcription By RNA Polymerase I Positive Regulation Of RRNA Processing
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Allergic rhinitis ( 30013184) Asthma ( 31959851 31619474 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Bipolar disorder ( 31043756) Body shape index ( 34021172) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) FEV1 ( 30804560) Keratoconus ( 33649486) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Proportion of activated microglia (midfrontal cortex) ( 30679421) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Post bronchodilator FEV1/FVC ratio ( 26634245) Total cholesterol levels ( 30275531)
Interacting Genes		10 interacting genes: AP1G1 AP1G2 AP1S3 AP2A1 AP2A2 AP2S1 BBS4 EIF3C HEATR1 UNC119	4 interacting genes: AAGAB VPS52 XRN1 YIF1A
Entrez ID		79719	55127
HPRD ID		07754	10962
Ensembl ID		ENSG00000103591	ENSG00000119285
Uniprot IDs		Q6PD74	A2VDI1 B2RWN5 Q9H583
PDB IDs
Enriched GO Terms of Interacting Partners?
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