HEATR1 and AAGAB

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		HEATR1	AAGAB
Description		HEAT repeat containing 1	alpha and gamma adaptin binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus Mitochondrion Membrane 90S Preribosome Small-subunit Processome T-UTP Complex	Cytoplasm Cytosol Nuclear Speck
	Molecular Function	RNA Binding Protein Binding SnoRNA Binding	Protein Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Positive Regulation Of Transcription By RNA Polymerase I Positive Regulation Of RRNA Processing	Protein Transport
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio ( 26634245) Total cholesterol levels ( 30275531)	Allergic rhinitis ( 30013184) Asthma ( 31959851 31619474 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Bipolar disorder ( 31043756) Body shape index ( 34021172) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) FEV1 ( 30804560) Keratoconus ( 33649486) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Proportion of activated microglia (midfrontal cortex) ( 30679421) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		4 interacting genes: AAGAB VPS52 XRN1 YIF1A	10 interacting genes: AP1G1 AP1G2 AP1S3 AP2A1 AP2A2 AP2S1 BBS4 EIF3C HEATR1 UNC119
Entrez ID		55127	79719
HPRD ID		10962	07754
Ensembl ID		ENSG00000119285	ENSG00000103591
Uniprot IDs		A2VDI1 B2RWN5 Q9H583	Q6PD74
PDB IDs
Enriched GO Terms of Interacting Partners?
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