AAGAB and AP1S3

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid)

		AAGAB	AP1S3
Description		alpha and gamma adaptin binding protein	adaptor related protein complex 1 subunit sigma 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Nuclear Speck	Golgi Membrane Lysosomal Membrane Cytosol Clathrin-coated Pit AP-1 Adaptor Complex Cytoplasmic Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding Clathrin Adaptor Activity
	Biological Process	Protein Transport	Protein Targeting Vesicle-mediated Transport
Pathways			Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Allergic rhinitis ( 30013184) Asthma ( 31959851 31619474 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Bipolar disorder ( 31043756) Body shape index ( 34021172) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) FEV1 ( 30804560) Keratoconus ( 33649486) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Proportion of activated microglia (midfrontal cortex) ( 30679421) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Airway wall thickness ( 25517131) Asthma ( 30929738 32296059) Asthma (childhood onset) ( 30929738) Initial alcohol sensitivity ( 30276832) Night sleep phenotypes ( 27126917) Sodium levels ( 29403010)
Interacting Genes		10 interacting genes: AP1G1 AP1G2 AP1S3 AP2A1 AP2A2 AP2S1 BBS4 EIF3C HEATR1 UNC119	2 interacting genes: AAGAB PRKAG1
Entrez ID		79719	130340
HPRD ID		07754	16495
Ensembl ID		ENSG00000103591	ENSG00000152056
Uniprot IDs		Q6PD74	Q96PC3
PDB IDs			4HMY 6CM9 6CRI 6D83 6D84 6DFF
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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