LENG1 and SPATA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LENG1	SPATA2
Description		leukocyte receptor cluster member 1	spermatogenesis associated 2
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Fibrillar Center Nucleoplasm Cytoplasm
	Molecular Function	Molecular_function Protein Binding	Protein Binding Signaling Receptor Complex Adaptor Activity Protein-containing Complex Binding Ubiquitin-specific Protease Binding
	Biological Process	Biological_process	Spermatogenesis Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Inflammatory Response Regulation Of Necroptotic Process Necroptotic Process Protein K63-linked Deubiquitination Seminiferous Tubule Development Protein Linear Deubiquitination
Pathways
Drugs
Diseases
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)	Coronary artery disease ( 29212778) Gut microbiota (beta diversity) ( 27723756) Psoriasis ( 20953189 25574825 18364390)
Interacting Genes		84 interacting genes: ABI2 APP ASB12 BANP BEGAIN C14orf119 CALCOCO2 CARD10 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCHCR1 CDR2 CDR2L CEP57L1 CEP70 DDIT4L DES DISC1 EVI5 FSD2 GFAP GOLGA2 GOLGA6L9 HOMEZ HOOK2 IKZF3 ISY1-RAB43 KANK2 KASH5 KIFC3 KLF10 KRT19 KRT31 KRT35 KRT40 KRTAP10-8 LDOC1 LRP2BP LZTS1 MAB21L3 MAD1L1 MEIS3 MID2 MIPOL1 MRPL28 MTUS2 NAB2 NAGK NECAB2 NTAQ1 NUTF2 OIP5 OSGEP PAK5 PDE4DIP PNMA1 PRKAR1B PRPH PSMB1 RABEP1 REL ROPN1 SCYL1 SPATA2 STX11 TCF4 TEPSIN TEX12 TFIP11 TMEM239 TRAF2 TRIB3 TRIM23 TRIM27 TRIM54 TSC1 UBL5 UBXN11 USHBP1 ZMYND12 ZRANB1	22 interacting genes: ANKRD11 APP ATP6V1H C2CD6 CCDC102B CEP72 DUT EFHC1 GOLGA2 GPANK1 KAT5 KIFC3 LENG1 MAD1L1 OTULIN PTPN6 RNF31 TBC1D22B TNIP1 TRAF2 TRIM27 ZNF835
Entrez ID		79165	9825
HPRD ID		13985	09636
Ensembl ID		ENSG00000105617	ENSG00000158480
Uniprot IDs		Q96BZ8	A8K0S9 B4DID4 Q9UM82
PDB IDs			5LJM 5LJN
Enriched GO Terms of Interacting Partners?
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