LENG1 and MEIS3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LENG1	MEIS3
Description		leukocyte receptor cluster member 1	Meis homeobox 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component	Chromatin Nucleus
	Molecular Function	Molecular_function Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Biological_process	Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Cell Population Proliferation Embryonic Pattern Specification Animal Organ Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		84 interacting genes: ABI2 APP ASB12 BANP BEGAIN C14orf119 CALCOCO2 CARD10 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCHCR1 CDR2 CDR2L CEP57L1 CEP70 DDIT4L DES DISC1 EVI5 FSD2 GFAP GOLGA2 GOLGA6L9 HOMEZ HOOK2 IKZF3 ISY1-RAB43 KANK2 KASH5 KIFC3 KLF10 KRT19 KRT31 KRT35 KRT40 KRTAP10-8 LDOC1 LRP2BP LZTS1 MAB21L3 MAD1L1 MEIS3 MID2 MIPOL1 MRPL28 MTUS2 NAB2 NAGK NECAB2 NTAQ1 NUTF2 OIP5 OSGEP PAK5 PDE4DIP PNMA1 PRKAR1B PRPH PSMB1 RABEP1 REL ROPN1 SCYL1 SPATA2 STX11 TCF4 TEPSIN TEX12 TFIP11 TMEM239 TRAF2 TRIB3 TRIM23 TRIM27 TRIM54 TSC1 UBL5 UBXN11 USHBP1 ZMYND12 ZRANB1	22 interacting genes: ATXN1L CCDC116 ENKD1 FAM110A FAM110B FAM161B FAM90A1 HGS HOXA13 INTS4 LENG1 LMO3 MBD3 PIP4K2A PRPF31 PSORS1C2 SUOX TCL1B TLE5 TSGA10IP VEZF1 ZNF417
Entrez ID		79165	56917
HPRD ID		13985	14386
Ensembl ID		ENSG00000105617	ENSG00000105419
Uniprot IDs		Q96BZ8	A0A024R0S2 A0A024R0W2 H0YNA8 Q49A38 Q99687
PDB IDs
Enriched GO Terms of Interacting Partners?
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