LENG1 and RABEP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LENG1	RABEP1
Description		leukocyte receptor cluster member 1	rabaptin, RAB GTPase binding effector protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Endosome Early Endosome Endocytic Vesicle Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	Molecular_function Protein Binding	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Biological_process	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Regulation Of Catalytic Activity Membrane Fusion Protein Localization To Ciliary Membrane
Pathways			TBC/RABGAPs
Drugs
Diseases
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)	Body mass index ( 28892062 25673413) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)
Interacting Genes		84 interacting genes: ABI2 APP ASB12 BANP BEGAIN C14orf119 CALCOCO2 CARD10 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCHCR1 CDR2 CDR2L CEP57L1 CEP70 DDIT4L DES DISC1 EVI5 FSD2 GFAP GOLGA2 GOLGA6L9 HOMEZ HOOK2 IKZF3 ISY1-RAB43 KANK2 KASH5 KIFC3 KLF10 KRT19 KRT31 KRT35 KRT40 KRTAP10-8 LDOC1 LRP2BP LZTS1 MAB21L3 MAD1L1 MEIS3 MID2 MIPOL1 MRPL28 MTUS2 NAB2 NAGK NECAB2 NTAQ1 NUTF2 OIP5 OSGEP PAK5 PDE4DIP PNMA1 PRKAR1B PRPH PSMB1 RABEP1 REL ROPN1 SCYL1 SPATA2 STX11 TCF4 TEPSIN TEX12 TFIP11 TMEM239 TRAF2 TRIB3 TRIM23 TRIM27 TRIM54 TSC1 UBL5 UBXN11 USHBP1 ZMYND12 ZRANB1	59 interacting genes: ABI2 AIMP2 AP1G1 AP1G2 ATXN7 BARD1 CASP3 CCDC120 CCND1 CDC73 CDK18 CDKL3 CEP57 CFAP53 DDX3X ELOA ESCO2 FAM50B FAM90A1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 LENG1 MAT2B MCRS1 ODAD3 PELI2 PKP2 PRPF3 RAB1A RAB33B RAB4A RAB4B RAB5A RABGEF1 RGS17 RNF39 SMURF1 SNAPIN SNW1 SRPK2 STAR TNS4 TRAPPC2L TRIM26 TSC2 TSHZ2 UBC UBTFL1 USP2 UTP14C WASHC3 YWHAG ZNF438 ZNF512B ZNF774
Entrez ID		79165	9135
HPRD ID		13985	04684
Ensembl ID		ENSG00000105617	ENSG00000029725
Uniprot IDs		Q96BZ8	B4DMM4 Q15276
PDB IDs			1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?
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