PRRC2A and PRMT2

Number of citations of the paper that reports this interaction (PubMedID 14667819)
36

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PRRC2A	PRMT2
Description		proline rich coiled-coil 2A	protein arginine methyltransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Membrane Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding	Transcription Coactivator Activity Protein Binding Histone-arginine N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Estrogen Receptor Binding Progesterone Receptor Binding Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Protein Homodimerization Activity Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Protein-containing Complex Binding Thyroid Hormone Receptor Binding Androgen Receptor Binding
	Biological Process	Cell Differentiation	Protein Methylation Signal Transduction Histone Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of NF-kappaB Transcription Factor Activity Histone Arginine Methylation Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Developmental Cell Growth Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 34211149) Anxiety ( 33859377) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood metabolite ratios ( 24816252) Blood protein levels ( 28240269) Body shape index ( 34021172) Childhood body mass index ( 33045005) Hand grip strength ( 29691431) Height ( 28552196) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Leukocyte telomere length ( 32109421) Malaria ( 31844061) Menopause (age at onset) ( 22267201) Metabolite levels ( 31628463) Platelet distribution width ( 32888494) Schizophrenia ( 23894747) Systolic blood pressure ( 30578418) Ulcerative colitis ( 28067908) Waist circumference ( 31928498) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Diverticular disease ( 30177863)
Interacting Genes		28 interacting genes: ATN1 ATXN1 C1QBP CCR10 CPSF1 DDX20 EIF3E EWSR1 FGA GANAB GORASP2 GRB2 HNRNPA1 HNRNPM IFT88 IMMT JUN MAD2L2 MAN2C1 P4HA2 PRMT2 PSMA3 QARS1 RBFOX1 RERE SRPK2 SSR3 UBAP2L	26 interacting genes: BAG6 CBLB CHEK2 CPSF7 DMRTB1 ERG ESR1 ESR2 FIP1L1 HNRNPA1 HNRNPUL1 NCOA1 NCOA6 PGR PRMT8 PRRC2A PSMB3 RB1 RBM12 RIPK2 RXRA SHANK3 SPAG8 THRB WASL ZNF341
Entrez ID		7916	3275
HPRD ID		00807	09060
Ensembl ID		ENSG00000204469	ENSG00000160310
Uniprot IDs		A0A1U9X974 P48634	A0A0S2Z3N3 P55345
PDB IDs			1X2P
Enriched GO Terms of Interacting Partners?
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