PRRC2A and P4HA2

Number of citations of the paper that reports this interaction (PubMedID 14667819)
36

Data Source:
HPRD (two hybrid)

		PRRC2A	P4HA2
Description		proline rich coiled-coil 2A	prolyl 4-hydroxylase subunit alpha 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Membrane Extracellular Exosome	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Electron Transfer Activity L-ascorbic Acid Binding
	Biological Process	Cell Differentiation	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Electron Transport Chain
Pathways			Collagen biosynthesis and modifying enzymes
Drugs			Proline
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 34211149) Anxiety ( 33859377) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood metabolite ratios ( 24816252) Blood protein levels ( 28240269) Body shape index ( 34021172) Childhood body mass index ( 33045005) Hand grip strength ( 29691431) Height ( 28552196) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Leukocyte telomere length ( 32109421) Malaria ( 31844061) Menopause (age at onset) ( 22267201) Metabolite levels ( 31628463) Platelet distribution width ( 32888494) Schizophrenia ( 23894747) Systolic blood pressure ( 30578418) Ulcerative colitis ( 28067908) Waist circumference ( 31928498) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Blood protein levels ( 29875488) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908 22412388) Giant cell arteritis ( 28041642) Height ( 28552196) Inflammatory bowel disease ( 28067908) Intracranial aneurysm ( 33199917) Intraocular pressure ( 29617998) Subcortical volume (MOSTest) ( 32665545) Sum eosinophil basophil counts ( 27863252) Ulcerative colitis ( 28067908) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		28 interacting genes: ATN1 ATXN1 C1QBP CCR10 CPSF1 DDX20 EIF3E EWSR1 FGA GANAB GORASP2 GRB2 HNRNPA1 HNRNPM IFT88 IMMT JUN MAD2L2 MAN2C1 P4HA2 PRMT2 PSMA3 QARS1 RBFOX1 RERE SRPK2 SSR3 UBAP2L	9 interacting genes: CD86 CLNK CREB3 FHL3 OGT P4HB PRKAR2A PRRC2A TNS4
Entrez ID		7916	8974
HPRD ID		00807	11862
Ensembl ID		ENSG00000204469	ENSG00000072682
Uniprot IDs		A0A1U9X974 P48634	O15460 Q05DA4
PDB IDs			6EVL 6EVM 6EVN 6EVO 6EVP
Enriched GO Terms of Interacting Partners?
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