PRMT2 and RBM12

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid)

		PRMT2	RBM12
Description		protein arginine methyltransferase 2	RNA binding motif protein 12
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol	Nucleoplasm Ribonucleoprotein Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Histone-arginine N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Estrogen Receptor Binding Progesterone Receptor Binding Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Protein Homodimerization Activity Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Protein-containing Complex Binding Thyroid Hormone Receptor Binding Androgen Receptor Binding	RNA Binding Protein Binding
	Biological Process	Protein Methylation Signal Transduction Histone Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of NF-kappaB Transcription Factor Activity Histone Arginine Methylation Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Developmental Cell Growth Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of RNA Splicing
Pathways
Drugs
Diseases
GWAS		Diverticular disease ( 30177863)	Blood protein levels ( 28240269) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		26 interacting genes: BAG6 CBLB CHEK2 CPSF7 DMRTB1 ERG ESR1 ESR2 FIP1L1 HNRNPA1 HNRNPUL1 NCOA1 NCOA6 PGR PRMT8 PRRC2A PSMB3 RB1 RBM12 RIPK2 RXRA SHANK3 SPAG8 THRB WASL ZNF341	5 interacting genes: BRAP GIGYF2 OPTN PRMT2 TBC1D4
Entrez ID		3275	10137
HPRD ID		09060	06212
Ensembl ID		ENSG00000160310	ENSG00000244462
Uniprot IDs		A0A0S2Z3N3 P55345	Q9NTZ6
PDB IDs		1X2P	1WEL 2CPY 2DNN 2EK1 2EK6
Enriched GO Terms of Interacting Partners?
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