TRAPPC6A and CTDSP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRAPPC6A	CTDSP1
Description		trafficking protein particle complex subunit 6A	CTD small phosphatase 1
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex	Nucleus Nucleoplasm Extracellular Exosome
	Molecular Function	Protein Binding	Phosphoprotein Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity Melanosome Assembly	Negative Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Protein Dephosphorylation Negative Regulation Of Neuron Differentiation Negative Regulation Of Neurogenesis Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		S-palmitoyl-L-cysteine	Aspartate beryllium trifluoride Citric acid
Diseases
GWAS		Alanine aminotransferase levels ( 33339817) Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Aspartate aminotransferase levels ( 33339817) Cerebrospinal fluid AB1-42 levels ( 28247064)	Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 23128233) Mean corpuscular hemoglobin concentration ( 32888494 27863252)
Interacting Genes		47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2	42 interacting genes: ACTN3 BAG3 CDCA3 CDKN2C CRYBA2 CSF1R CSTF2T FAAP20 FAM110A FANCL FGFR2 GPSM1 GTF2F1 ITPKB LCK LDB1 LRRC73 LTBP4 MAPKBP1 MBP MORN3 NOXA1 OSTF1 PDZD4 PLEKHM1 POLR2A PPP1R32 PTPN11 RAB3IL1 RPRD2 SCNM1 SDCBP SNAI1 STRA8 TEKT4 TRAPPC6A TYRO3 USP29 WWOX YPEL5 ZBTB16 ZSWIM8
Entrez ID		79090	58190
HPRD ID		14503	05615
Ensembl ID		ENSG00000007255	ENSG00000144579
Uniprot IDs		B7TZ90 O75865	Q9GZU7
PDB IDs		2C0J 2J3T	1T9Z 1TA0 2GHQ 2GHT 3L0B 3L0C 3L0Y 3PGL 4YGY 4YH1 6DU3
Enriched GO Terms of Interacting Partners?
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