CTDSP1 and ZSWIM8

Number of citations of the paper that reports this interaction (PubMedID 21653829)
98

Data Source:
BioGRID (two hybrid)

		CTDSP1	ZSWIM8
Description		CTD small phosphatase 1	zinc finger SWIM-type containing 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Extracellular Exosome	Cytosol Cul2-RING Ubiquitin Ligase Complex Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Zinc Ion Binding Ubiquitin Ligase-substrate Adaptor Activity
	Biological Process	Negative Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Protein Dephosphorylation Negative Regulation Of Neuron Differentiation Negative Regulation Of Neurogenesis Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of MiRNA Catabolic Process
Pathways			Regulation of expression of SLITs and ROBOs
Drugs		Aspartate beryllium trifluoride Citric acid
Diseases
GWAS		Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 23128233) Mean corpuscular hemoglobin concentration ( 32888494 27863252)	Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Crohn's disease ( 28067908)
Interacting Genes		42 interacting genes: ACTN3 BAG3 CDCA3 CDKN2C CRYBA2 CSF1R CSTF2T FAAP20 FAM110A FANCL FGFR2 GPSM1 GTF2F1 ITPKB LCK LDB1 LRRC73 LTBP4 MAPKBP1 MBP MORN3 NOXA1 OSTF1 PDZD4 PLEKHM1 POLR2A PPP1R32 PTPN11 RAB3IL1 RPRD2 SCNM1 SDCBP SNAI1 STRA8 TEKT4 TRAPPC6A TYRO3 USP29 WWOX YPEL5 ZBTB16 ZSWIM8	4 interacting genes: ATN1 ATXN1 ATXN1L CTDSP1
Entrez ID		58190	23053
HPRD ID		05615	17199
Ensembl ID		ENSG00000144579	ENSG00000214655
Uniprot IDs		Q9GZU7	A7E2V4
PDB IDs		1T9Z 1TA0 2GHQ 2GHT 3L0B 3L0C 3L0Y 3PGL 4YGY 4YH1 6DU3
Enriched GO Terms of Interacting Partners?
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