IFRD2 and OAS3

Number of citations of the paper that reports this interaction (PubMedID 21903422)
143

Data Source:
BioGRID (affinity chromatography technology, pull down)

		IFRD2	OAS3
Description		interferon related developmental regulator 2	2'-5'-oligoadenylate synthetase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Space Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Molecular_function Protein Binding	2'-5'-oligoadenylate Synthetase Activity Double-stranded RNA Binding Protein Binding ATP Binding Metal Ion Binding
	Biological Process		Nucleobase-containing Compound Metabolic Process Response To Virus Positive Regulation Of Interferon-beta Production Positive Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Chemokine (C-X-C Motif) Ligand 9 Production RIG-I Signaling Pathway MDA-5 Signaling Pathway Defense Response To Bacterium Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Ribonuclease Activity Positive Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of Chemokine (C-C Motif) Ligand 5 Production Negative Regulation Of IP-10 Production Negative Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Pathways			Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Alcohol consumption ( 21270382) Alcohol consumption (drinkers vs non-drinkers) ( 28485404) Body mass index ( 26426971) Chronic lymphocytic leukemia ( 28165464) HDL cholesterol ( 21909109) High density lipoprotein cholesterol levels ( 30718733) Hypertension ( 32709000) Low HDL-cholesterol levels ( 31006500) Myocardial infarction ( 30226566) Response to fenofibrate (adiponectin levels) ( 23149075) Right-sided colonic diverticulosis ( 31089239)
Interacting Genes		7 interacting genes: APP JRK MDFI NEDD4L OAS3 OGT POT1	5 interacting genes: DHX30 EIF6 FTSJ3 IFRD2 MAVS
Entrez ID		7866	4940
HPRD ID		04101	04519
Ensembl ID		ENSG00000214706	ENSG00000111331
Uniprot IDs		Q12894	Q9Y6K5
PDB IDs			4S3N
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?