MALL and FCGR1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MALL	FCGR1A
Description		mal, T cell differentiation protein like	Fc fragment of IgG receptor Ia
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Raft	Plasma Membrane Integral Component Of Plasma Membrane Clathrin-coated Endocytic Vesicle Membrane Early Endosome Membrane
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Transmembrane Signaling Receptor Activity Protein Binding IgG Binding
	Biological Process	Myelination Cholesterol Homeostasis	Phagocytosis, Engulfment Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Innate Immune Response Regulation Of Immune Response Positive Regulation Of Protein Tyrosine Kinase Activity
Pathways			Cross-presentation of soluble exogenous antigens (endosomes) Cross-presentation of soluble exogenous antigens (endosomes) Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell FCGR activation FCGR activation Regulation of actin dynamics for phagocytic cup formation Role of phospholipids in phagocytosis Interferon gamma signaling FCGR3A-mediated IL10 synthesis
Drugs			Cetuximab Etanercept Human immunoglobulin G Gemtuzumab ozogamicin Alemtuzumab Natalizumab Palivizumab Daclizumab Bevacizumab Porfimer sodium Catumaxomab Sarilumab Trastuzumab deruxtecan
Diseases
GWAS
Interacting Genes		70 interacting genes: AMIGO1 AQP6 ARL13B ATP5PF BEST2 BNIP3 BNIP3L BRI3 BSCL2 CAV1 CAV2 CD79A CLDN7 CLDN9 CLEC10A CLEC12B CLEC14A CPLX4 CREB3 CREB3L1 CRHR2 CTLA4 DAGLA DCBLD2 ELOVL2 ELOVL4 EMP1 EVI2A FCGR1A FFAR2 FNDC9 GGT7 GJA8 GPA33 IL7R KASH5 KLRC1 LDLRAD1 LEPROTL1 LMNA MANBAL MCEMP1 MS4A12 MSR1 MUC1 NEK9 OPRM1 PGRMC2 PLA2G2E RETREG3 RNF185 SIGLEC6 SIT1 SLC10A1 SLC10A6 SLC18A1 SLC35C2 STMN4 STX1A SYNE4 SYT2 TMEM139 TMEM182 TMEM248 TMEM31 TMEM80 TMX2 UBE2I VPS11 ZP3	30 interacting genes: ADIPOQ APCS ASGR1 BIK BMP10 CD163 CLDN19 CLEC7A CRKL CRP FAM3C FCAR FCGR3A HCK HRG ITM2A JAGN1 LAT LHFPL5 LILRB2 MALL NINJ1 NRSN1 RPRM SYK TNMD TSPO2 UPK2 VSTM1 VTI1B
Entrez ID		7851	2209
HPRD ID		15997	00904
Ensembl ID		ENSG00000144063	ENSG00000150337
Uniprot IDs		Q13021	P12314
PDB IDs			3RJD 4W4O 4X4M 4ZNE
Enriched GO Terms of Interacting Partners?
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