MALL and CRHR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MALL	CRHR2
Description		mal, T cell differentiation protein like	corticotropin releasing hormone receptor 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Raft	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Axon Terminus
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Protein Binding G Protein-coupled Peptide Receptor Activity Corticotrophin-releasing Factor Receptor Activity Peptide Hormone Binding Corticotropin-releasing Hormone Receptor Activity
	Biological Process	Myelination Cholesterol Homeostasis	Cell Surface Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Hormone-mediated Signaling Pathway Long-term Synaptic Potentiation Cellular Response To Corticotropin-releasing Hormone Stimulus
Pathways			G alpha (s) signalling events Synthesis, secretion, and deacylation of Ghrelin ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS			Type 2 diabetes ( 24509480 30297969)
Interacting Genes		70 interacting genes: AMIGO1 AQP6 ARL13B ATP5PF BEST2 BNIP3 BNIP3L BRI3 BSCL2 CAV1 CAV2 CD79A CLDN7 CLDN9 CLEC10A CLEC12B CLEC14A CPLX4 CREB3 CREB3L1 CRHR2 CTLA4 DAGLA DCBLD2 ELOVL2 ELOVL4 EMP1 EVI2A FCGR1A FFAR2 FNDC9 GGT7 GJA8 GPA33 IL7R KASH5 KLRC1 LDLRAD1 LEPROTL1 LMNA MANBAL MCEMP1 MS4A12 MSR1 MUC1 NEK9 OPRM1 PGRMC2 PLA2G2E RETREG3 RNF185 SIGLEC6 SIT1 SLC10A1 SLC10A6 SLC18A1 SLC35C2 STMN4 STX1A SYNE4 SYT2 TMEM139 TMEM182 TMEM248 TMEM31 TMEM80 TMX2 UBE2I VPS11 ZP3	8 interacting genes: APP CRH GCC1 GPR35 MALL UCN UCN2 UCN3
Entrez ID		7851	1395
HPRD ID		15997	03614
Ensembl ID		ENSG00000144063	ENSG00000106113
Uniprot IDs		Q13021	A0A090N7T4 Q13324
PDB IDs			3N93 3N95 3N96 6PB1
Enriched GO Terms of Interacting Partners?
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