PHLDA2 and FCHO1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PHLDA2	FCHO1
Description		pleckstrin homology like domain family A member 2	FCH and mu domain containing endocytic adaptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle
	Molecular Function	Protein Binding Phosphatidylinositol Phosphate Binding	Protein Binding AP-2 Adaptor Complex Binding
	Biological Process	Placenta Development Apoptotic Process Animal Organ Morphogenesis Regulation Of Gene Expression Regulation Of Cell Migration Positive Regulation Of Apoptotic Process Regulation Of Embryonic Development Regulation Of Spongiotrophoblast Cell Proliferation Regulation Of Glycogen Metabolic Process Regulation Of Growth Hormone Activity	Clathrin Coat Assembly Clathrin-dependent Endocytosis
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Calcium levels ( 20705733) Malaria ( 31844061)	Basophil count ( 32888494) Coronary artery disease ( 29212778) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Monocyte percentage of white cells ( 32888494) Myocardial infarction ( 33532862)
Interacting Genes		6 interacting genes: FCHO1 HSP90AA1 OTUB2 SSX2 SSX2B TH	52 interacting genes: ACVR1 APP BYSL CCDC13 CSNK2A1 CWF19L2 DAB2 DDX6 DNAJC5 ELOA EPS15 EPS15L1 EXOSC5 FBXL7 GDF15 GRB7 GUCD1 ITSN1 KAT5 KPRP KRTAP10-1 KRTAP10-5 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP4-12 KRTAP6-1 KRTAP6-3 LGALS14 MAB21L3 NCK1 PCGF1 PHETA1 PHLDA2 PICALM PLAC8 PLSCR4 PRPF3 PRPH PTK6 SH2D4A SMURF1 SRPK2 SYTL4 TCEA2 TCEANC TGFB1 TRIM42 TSPAN4 ZBTB16 ZBTB24 ZNF688
Entrez ID		7262	23149
HPRD ID		03679	16887
Ensembl ID		ENSG00000181649	ENSG00000130475
Uniprot IDs		Q53GA4	A0A0C3SFZ9 B7ZAZ3 O14526
PDB IDs
Enriched GO Terms of Interacting Partners?
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