FCHO1 and PHLDA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FCHO1	PHLDA2
Description		FCH and mu domain containing endocytic adaptor 1	pleckstrin homology like domain family A member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle	Cytoplasm Membrane
	Molecular Function	Protein Binding AP-2 Adaptor Complex Binding	Protein Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Clathrin Coat Assembly Clathrin-dependent Endocytosis	Placenta Development Apoptotic Process Animal Organ Morphogenesis Regulation Of Gene Expression Regulation Of Cell Migration Positive Regulation Of Apoptotic Process Regulation Of Embryonic Development Regulation Of Spongiotrophoblast Cell Proliferation Regulation Of Glycogen Metabolic Process Regulation Of Growth Hormone Activity
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Basophil count ( 32888494) Coronary artery disease ( 29212778) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Monocyte percentage of white cells ( 32888494) Myocardial infarction ( 33532862)	Calcium levels ( 20705733) Malaria ( 31844061)
Interacting Genes		52 interacting genes: ACVR1 APP BYSL CCDC13 CSNK2A1 CWF19L2 DAB2 DDX6 DNAJC5 ELOA EPS15 EPS15L1 EXOSC5 FBXL7 GDF15 GRB7 GUCD1 ITSN1 KAT5 KPRP KRTAP10-1 KRTAP10-5 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP4-12 KRTAP6-1 KRTAP6-3 LGALS14 MAB21L3 NCK1 PCGF1 PHETA1 PHLDA2 PICALM PLAC8 PLSCR4 PRPF3 PRPH PTK6 SH2D4A SMURF1 SRPK2 SYTL4 TCEA2 TCEANC TGFB1 TRIM42 TSPAN4 ZBTB16 ZBTB24 ZNF688	6 interacting genes: FCHO1 HSP90AA1 OTUB2 SSX2 SSX2B TH
Entrez ID		23149	7262
HPRD ID		16887	03679
Ensembl ID		ENSG00000130475	ENSG00000181649
Uniprot IDs		A0A0C3SFZ9 B7ZAZ3 O14526	Q53GA4
PDB IDs
Enriched GO Terms of Interacting Partners?
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