Description |
Bruton tyrosine kinase |
FYN proto-oncogene, Src family tyrosine kinase |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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Interacting Genes |
78 interacting genes:
ABL1
APP
AR
ARHGAP17
ARID3A
ARRB1
AURKA
BCL2L11
BECN1
BLNK
BMX
CAV1
CBL
CD19
CMTM3
COASY
DAPP1
ERBB3
EWSR1
FAS
FASLG
FYN
GAB1
GNA12
GNAQ
GNB1
GNG2
GTF2I
HCK
IBTK
IRAK1
ITK
JAK1
KHDRBS1
KIT
LYN
MDM2
MEOX2
MET
MRPS22
MYD88
PIK3AP1
PIK3R3
PIP4K2A
PIP4K2B
PIP4K2C
PIP5K1A
PIP5K1B
PIP5K1C
PLAU
PLCG1
PLCG2
PRKCA
PRKCB
PRKCE
PRKCQ
PRKCZ
PRKD1
RELA
RPS6KB1
RPS6KB2
SH2B2
SH3BP5
SMURF1
STAT5A
SYK
TEC
TIRAP
TLR4
TLR6
TLR8
TLR9
TNFRSF10A
TNFRSF18
TP53
VAV1
WAS
WASF2
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200 interacting genes:
ACP1
ADAM15
ADD2
ARHGAP32
ARHGAP33
ATXN1
BAG4
BCAR1
BCL3
BTK
C7orf25
C8orf33
CASP3
CASP8
CAV1
CBL
CBLB
CBLC
CD19
CD2
CD226
CD247
CD2AP
CD36
CD44
CD48
CD5
CD55
CD79A
CD79B
CDH1
CDK1
CDK5
CLTC
CMA1
CNN1
CNN3
CNTN1
CNTNAP1
CRK
CSF1R
CSF2RB
CSK
CTLA4
CTNNB1
CTNND2
DAG1
DLG4
DLGAP4
DOK1
DOK3
DOK4
DTX3
EFS
ENO1
EPHA3
EPHA4
EPHA8
EPHB3
ERRFI1
EVL
FAM90A1
FAS
FASLG
FCER2
FCGR2A
FLOT1
FLOT2
FLT1
FNBP4
FYB1
GAB3
GP6
GRAP
GRB10
GRB2
GRIN1
GRIN2A
GRIN2B
HDAC2
HNRNPK
HRAS
HSP90AA1
HTR6
IGHA1
IL1B
IL2RB
IL7R
IRS1
ITCH
ITGB4
ITK
ITPR1
JAK2
JUP
KDM1A
KDR
KHDRBS1
KIT
LAT
LCK
LCP2
MAG
MAP2
MAPT
MCAM
MED28
MEOX2
MS4A1
NCAM1
NEDD4
NEDD9
NMT1
NOS1AP
NPHS1
NR3C1
NTRK2
PAG1
PAK2
PDE4D
PDGFRB
PECAM1
PIK3R1
PIK3R2
PIK3R3
PLAUR
PLCG1
PLCG2
PLD2
PRKCD
PRKCE
PRKCH
PRKCQ
PRKCZ
PRMT6
PRMT8
PRRG4
PTK2
PTK2B
PTPN11
PTPN5
PTPRA
PTPRC
PTPRE
PTPRF
PTPRZ1
PXN
RACK1
RAF1
RPL10
RPS6KA3
RPS6KB2
SDC3
SH2B2
SH2D1A
SH3BP2
SHC1
SIT1
SKAP1
SKAP2
SLAMF1
SNCA
SOCS1
SOS1
SPHK1
SPHK2
SPN
STAT1
STAT3
SUV39H1
SYK
TAMALIN
TCAP
THY1
TNF
TNK2
TNNT1
TOM1L1
TRAF6
TRAT1
TRIM55
TRIM63
TRPC6
TRPV4
TUBA1B
TUBA3C
TUBA4A
TXK
TYK2
TYRO3
UHRF2
UNC119
VAV1
VAV2
WAS
WASF1
WASF2
WBP11
YTHDC1
ZAP70
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Entrez ID |
695 |
2534 |
HPRD ID |
02248 |
00655 |
Ensembl ID |
ENSG00000010671
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ENSG00000010810
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Uniprot IDs |
Q06187
Q5JY90
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P06241
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PDB IDs |
1AWW
1AWX
1B55
1BTK
1BWN
1K2P
1QLY
2GE9
2Z0P
3GEN
3K54
3OCS
3OCT
3P08
3PIX
3PIY
3PIZ
3PJ1
3PJ2
3PJ3
4NWM
4OT5
4OT6
4OTF
4OTQ
4OTR
4RFY
4RFZ
4RG0
4RX5
4YHF
4Z3V
4ZLY
4ZLZ
5BPY
5BQ0
5FBN
5FBO
5J87
5JRS
5KUP
5P9F
5P9G
5P9H
5P9I
5P9J
5P9K
5P9L
5P9M
5T18
5U9D
5VFI
5VGO
5XYZ
5ZZ4
6AUA
6AUB
6BIK
6BKE
6BKH
6BKW
6BLN
6DI0
6DI1
6DI3
6DI5
6DI9
6E4F
6EP9
6HRP
6HRT
6HTF
6J6M
6N9P
6NFH
6NFI
6NZM
6O8I
6OMU
6S90
6TFP
6TSE
6TT2
6TUH
6TVN
6VXQ
6W06
6W07
6W7O
6W8I
6X3N
6X3O
6X3P
6XE4
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1A0N
1AOT
1AOU
1AVZ
1AZG
1EFN
1FYN
1G83
1M27
1NYF
1NYG
1SHF
1ZBJ
2DQ7
2MQI
2MRJ
2MRK
3H0F
3H0H
3H0I
3UA6
3UA7
4D8D
4EIK
4U17
4U1P
4ZNX
5ZAU
6EDF
6IPY
6IPZ
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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