Description |
Bruton tyrosine kinase |
phosphoinositide-3-kinase regulatory subunit 3 |
Image |
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No pdb structure |
GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Body mass index ( 26426971 28448500)
- Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
- Body mass index in physically active individuals ( 28448500)
- Brain morphology (min-P) ( 32665545)
- Brain morphology (MOSTest) ( 32665545)
- Breast cancer ( 29059683)
- Cortical surface area (min-P) ( 32665545)
- Cortical surface area (MOSTest) ( 32665545)
- Cortical thickness (min-P) ( 32665545)
- Cortical thickness (MOSTest) ( 32665545)
- Diastolic blood pressure ( 30224653)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
- Estimated glomerular filtration rate ( 31152163)
- Lymphocyte percentage of white cells ( 32888494)
- Metabolite levels ( 23823483)
- Neutrophil count ( 32888494)
- Neutrophil percentage of white cells ( 32888494)
- Red cell distribution width ( 32888494)
- Serum metabolite levels ( 33031748)
- Sodium levels ( 29403010)
- Subcortical volume (min-P) ( 32665545)
- Subcortical volume (MOSTest) ( 32665545)
- Sum neutrophil eosinophil counts ( 27863252)
- White blood cell count ( 32888494 27863252)
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Interacting Genes |
78 interacting genes:
ABL1
APP
AR
ARHGAP17
ARID3A
ARRB1
AURKA
BCL2L11
BECN1
BLNK
BMX
CAV1
CBL
CD19
CMTM3
COASY
DAPP1
ERBB3
EWSR1
FAS
FASLG
FYN
GAB1
GNA12
GNAQ
GNB1
GNG2
GTF2I
HCK
IBTK
IRAK1
ITK
JAK1
KHDRBS1
KIT
LYN
MDM2
MEOX2
MET
MRPS22
MYD88
PIK3AP1
PIK3R3
PIP4K2A
PIP4K2B
PIP4K2C
PIP5K1A
PIP5K1B
PIP5K1C
PLAU
PLCG1
PLCG2
PRKCA
PRKCB
PRKCE
PRKCQ
PRKCZ
PRKD1
RELA
RPS6KB1
RPS6KB2
SH2B2
SH3BP5
SMURF1
STAT5A
SYK
TEC
TIRAP
TLR4
TLR6
TLR8
TLR9
TNFRSF10A
TNFRSF18
TP53
VAV1
WAS
WASF2
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127 interacting genes:
ABCB6
ABL2
AMBP
ANKS1A
ANTKMT
AR
ARID4B
AUNIP
AXL
BLK
BLZF1
BRK1
BTK
C3orf36
C9orf24
CAMK1
CCDC14
CCDC196
CCDC33
CCDC89
CEP126
CEP19
CHRDL2
CLNK
CRBN
CRK
DARS1
DCAF8
DISC1
DRAP1
DSN1
E2F6
EGFR
ENKD1
ERBB2
ERBB3
ERBB4
ESR1
FAM166B
FBN3
FER
FGB
FNDC8
FOXO1
FSD2
FYN
GAB1
GC
GRB2
HROB
HSH2D
IGF1R
INSR
IPO13
IQUB
IRS1
IRS2
ITGB3BP
KARS1
KDM4A
KHDRBS1
KIAA0408
KIT
KLC2
KLF15
KMT2B
L3MBTL3
LAP3
LNX2
LUC7L2
MBIP
MECOM
MET
MICAL1
MTF2
NAB2
NCK1
NEBL
NEDD9
ORM1
PACRGL
PBX4
PCDHB5
PDGFRB
PELO
PIK3CA
PIK3CD
PLAAT4
PLB1
PLEKHF2
PPARA
PRKAR1B
PSME1
PTK2
QARS1
RB1
RING1
RUSC1
SERF1A
SERTAD2
SOCS6
SPATA32
SRC
SSBP4
ST3GAL3
STAT3
STAT5B
TASOR2
TEC
TERF2
TNK2
TNNC2
TNNI1
TRIM54
TRMT2A
TSPAN2
USP2
VBP1
VCP
WRNIP1
YES1
YPEL3
ZBTB18
ZMAT1
ZNF281
ZNF451
ZNF620
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Entrez ID |
695 |
8503 |
HPRD ID |
02248 |
05831 |
Ensembl ID |
ENSG00000010671
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ENSG00000117461
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Uniprot IDs |
Q06187
Q5JY90
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B4DXM8
Q68CY7
Q7Z3W2
Q8N381
Q92569
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PDB IDs |
1AWW
1AWX
1B55
1BTK
1BWN
1K2P
1QLY
2GE9
2Z0P
3GEN
3K54
3OCS
3OCT
3P08
3PIX
3PIY
3PIZ
3PJ1
3PJ2
3PJ3
4NWM
4OT5
4OT6
4OTF
4OTQ
4OTR
4RFY
4RFZ
4RG0
4RX5
4YHF
4Z3V
4ZLY
4ZLZ
5BPY
5BQ0
5FBN
5FBO
5J87
5JRS
5KUP
5P9F
5P9G
5P9H
5P9I
5P9J
5P9K
5P9L
5P9M
5T18
5U9D
5VFI
5VGO
5XYZ
5ZZ4
6AUA
6AUB
6BIK
6BKE
6BKH
6BKW
6BLN
6DI0
6DI1
6DI3
6DI5
6DI9
6E4F
6EP9
6HRP
6HRT
6HTF
6J6M
6N9P
6NFH
6NFI
6NZM
6O8I
6OMU
6S90
6TFP
6TSE
6TT2
6TUH
6TVN
6VXQ
6W06
6W07
6W7O
6W8I
6X3N
6X3O
6X3P
6XE4
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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