SPAG4 and ASGR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SPAG4	ASGR1
Description		sperm associated antigen 4	asialoglycoprotein receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Integral Component Of Nuclear Inner Membrane Cytoplasm Cytoskeleton Motile Cilium Meiotic Nuclear Membrane Microtubule Tethering Complex	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Protein-membrane Adaptor Activity	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Nuclear Envelope Organization Spermatogenesis Cell Differentiation	Receptor-mediated Endocytosis Cellular Response To Extracellular Stimulus
Pathways			Asparagine N-linked glycosylation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Apolipoprotein B levels ( 32203549) Iron status biomarkers (ferritin levels) ( 33536631) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514 22001757) Low density lipoprotein cholesterol levels ( 32154731 33339817) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 33547301 31666285 29403010 33339817) Total cholesterol levels ( 33339817)
Interacting Genes		24 interacting genes: ABHD16A ASGR1 BMP10 CSGALNACT1 ERMP1 GOSR2 IGFBP5 MS4A13 NRM ODF1 PAXIP1 PGA4 PLN PTPN9 RUSF1 SCAMP4 SCD SEC22A SUN5 TMEM187 TMEM60 TNMD TRARG1 TSPO2	44 interacting genes: AHNAK2 AMIGO1 APH1A APP ASGR2 ATP1B4 BLCAP CERS2 CLDN7 CLEC4G CPLX4 CREB3L1 CYB5R3 DHFR ERGIC3 FAM209A FCGR1A FNDC9 GPX8 HIBADH HIVEP1 HSP90AA1 HSP90B1 IGFBP5 KIR2DL3 LAMTOR5 LEUTX LMNA MCEMP1 NEMP1 NLK PDZK1IP1 PLS3 RBBP6 RNF19B SAR1A SLC10A1 SLC35C2 SPAG4 SUSD3 TG TMX2 VKORC1 VSIR
Entrez ID		6676	432
HPRD ID		04330	00151
Ensembl ID		ENSG00000061656	ENSG00000141505
Uniprot IDs		Q9NPE6	P07306 Q6FGQ5
PDB IDs			1DV8 5JPV 5JQ1 6YAU
Enriched GO Terms of Interacting Partners?
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