ASGR1 and TG

Number of citations of the paper that reports this interaction (PubMedID 12477859)
29

Data Source:
HPRD (in vivo)

		ASGR1	TG
Description		asialoglycoprotein receptor 1	thyroglobulin
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Extracellular Space
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Identical Protein Binding Metal Ion Binding	Hormone Activity Protein Binding Identical Protein Binding
	Biological Process	Receptor-mediated Endocytosis Cellular Response To Extracellular Stimulus	Thyroid Hormone Generation Signal Transduction Iodide Transport Thyroid Gland Development Regulation Of Myelination Hormone Biosynthetic Process
Pathways		Asparagine N-linked glycosylation
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Iron status biomarkers (ferritin levels) ( 33536631) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514 22001757) Low density lipoprotein cholesterol levels ( 32154731 33339817) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 33547301 31666285 29403010 33339817) Total cholesterol levels ( 33339817)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Asthma ( 34103634) Autoimmune thyroid disease ( 32581359) Bone erosion in rheumatoid arthritis ( 28512992) Brain morphology (MOSTest) ( 32665545) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Graves' disease ( 23612905) Hyperthyroidism ( 30367059) Hypothyroidism ( 27182965) Medication use (thyroid preparations) ( 31015401) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Temperament ( 22832960) Thyroid stimulating hormone levels ( 30367059) Vitiligo ( 27723757)
Interacting Genes		44 interacting genes: AHNAK2 AMIGO1 APH1A APP ASGR2 ATP1B4 BLCAP CERS2 CLDN7 CLEC4G CPLX4 CREB3L1 CYB5R3 DHFR ERGIC3 FAM209A FCGR1A FNDC9 GPX8 HIBADH HIVEP1 HSP90AA1 HSP90B1 IGFBP5 KIR2DL3 LAMTOR5 LEUTX LMNA MCEMP1 NEMP1 NLK PDZK1IP1 PLS3 RBBP6 RNF19B SAR1A SLC10A1 SLC35C2 SPAG4 SUSD3 TG TMX2 VKORC1 VSIR	10 interacting genes: APCS ASGR1 CANX CRYM CTSD CTSL HSP90B1 HSPA5 LRP2 P4HB
Entrez ID		432	7038
HPRD ID		00151	01782
Ensembl ID		ENSG00000141505	ENSG00000042832
Uniprot IDs		P07306 Q6FGQ5	P01266
PDB IDs		1DV8 5JPV 5JQ1 6YAU	6SCJ
Enriched GO Terms of Interacting Partners?
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