SPAG4 and ERMP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SPAG4	ERMP1
Description		sperm associated antigen 4	endoplasmic reticulum metallopeptidase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Integral Component Of Nuclear Inner Membrane Cytoplasm Cytoskeleton Motile Cilium Meiotic Nuclear Membrane Microtubule Tethering Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Protein-membrane Adaptor Activity	Protein Binding Metalloexopeptidase Activity Metal Ion Binding
	Biological Process	Nuclear Envelope Organization Spermatogenesis Cell Differentiation	Proteolysis Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Asthma ( 31959851 31619474) Blond vs. brown/black hair color ( 30531825) Waist-hip ratio ( 28552196)
Interacting Genes		24 interacting genes: ABHD16A ASGR1 BMP10 CSGALNACT1 ERMP1 GOSR2 IGFBP5 MS4A13 NRM ODF1 PAXIP1 PGA4 PLN PTPN9 RUSF1 SCAMP4 SCD SEC22A SUN5 TMEM187 TMEM60 TNMD TRARG1 TSPO2	38 interacting genes: AQP2 AQP6 ATP1B4 BCL2L13 BSCL2 CD200R1 CLDN5 CLDN7 CLDN9 CLEC2D CREB3L1 ERVFRD-1 FAM209A FNDC9 GJA8 GPR42 GPRC5D HHLA2 HIBADH IER3IP1 IFNGR2 KCNN3 KLRC1 LYPD5 MLANA MR1 PDCD1LG2 PEX12 RHCG SLC13A4 SLC22A23 SLC23A2 SLC7A14 SPAG4 SSMEM1 TMEM237 TMEM45A TMEM80
Entrez ID		6676	79956
HPRD ID		04330	17227
Ensembl ID		ENSG00000061656	ENSG00000099219
Uniprot IDs		Q9NPE6	Q6ZMD3 Q7Z2K6
PDB IDs
Enriched GO Terms of Interacting Partners?
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