SNX1 and REEP5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SNX1	REEP5
Description		sorting nexin 1	receptor accessory protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Vesicle Protein-containing Complex Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Integral Component Of Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding	Molecular_function Protein Binding
	Biological Process	Intracellular Protein Transport Receptor Internalization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Lamellipodium Morphogenesis	Endoplasmic Reticulum Organization Biological_process Regulation Of Intracellular Transport
Pathways			Olfactory Signaling Pathway
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057) Daytime nap ( 33568662) Reaction time ( 29844566)
Interacting Genes		48 interacting genes: ACVR1B ACVR2B AGTRAP APP ARFIP2 ARL6IP1 ARMC12 ATXN7 CCDC148 CHRNG CMTM4 CMTM5 COQ3 EGFR F2R FAM25A FAM25C FAM25G FKBP7 FUNDC1 HCCS HGS INSR LEPR LIME1 MPC2 PDGFRB PLIN3 RABAC1 REEP5 REEP6 RHEX RTN3 RTN4 SASH1 SDCBP SDR16C5 SFT2D1 SH3GLB1 SNX2 SNX32 SNX6 SYNGR1 SYP TK1 TMEM239 UFD1 VPS35	22 interacting genes: ABHD4 ARFGAP1 ARFIP2 CD14 CHRM5 CPOX EDC3 GPX3 GTF2H1 HBEGF LGR5 NUDT3 PBX3 PDK4 PDLIM3 PITPNC1 RAB5B RABAC1 RGS2 SNX1 TENT4A VKORC1
Entrez ID		6642	7905
HPRD ID		03171	15918
Ensembl ID		ENSG00000028528	ENSG00000129625
Uniprot IDs		Q13596	Q00765
PDB IDs		2I4K 4FZS
Enriched GO Terms of Interacting Partners?
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