SNX1 and MPC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SNX1	MPC2
Description		sorting nexin 1	mitochondrial pyruvate carrier 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Vesicle Protein-containing Complex Intracellular Membrane-bounded Organelle	Nucleus Mitochondrion Integral Component Of Mitochondrial Inner Membrane
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding	Protein Binding Identical Protein Binding Pyruvate Transmembrane Transporter Activity
	Biological Process	Intracellular Protein Transport Receptor Internalization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Lamellipodium Morphogenesis	Mitochondrial Pyruvate Transmembrane Transport Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Mitochondrial Acetyl-CoA Biosynthetic Process From Pyruvate
Pathways			Pyruvate metabolism
Drugs
Diseases
GWAS
Interacting Genes		48 interacting genes: ACVR1B ACVR2B AGTRAP APP ARFIP2 ARL6IP1 ARMC12 ATXN7 CCDC148 CHRNG CMTM4 CMTM5 COQ3 EGFR F2R FAM25A FAM25C FAM25G FKBP7 FUNDC1 HCCS HGS INSR LEPR LIME1 MPC2 PDGFRB PLIN3 RABAC1 REEP5 REEP6 RHEX RTN3 RTN4 SASH1 SDCBP SDR16C5 SFT2D1 SH3GLB1 SNX2 SNX32 SNX6 SYNGR1 SYP TK1 TMEM239 UFD1 VPS35	13 interacting genes: APOC1 CIDEB DIABLO MICOS10 MPC1 NEAT1 RHBDD2 RPLP1 SNX1 SPG21 SYT16 TEX44 TIMM17B
Entrez ID		6642	25874
HPRD ID		03171	08525
Ensembl ID		ENSG00000028528	ENSG00000143158
Uniprot IDs		Q13596	A0A024R8Z5 O95563
PDB IDs		2I4K 4FZS
Enriched GO Terms of Interacting Partners?
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