SNX1 and SNX32

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		SNX1	SNX32
Description		sorting nexin 1	sorting nexin 32
Image
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Vesicle Protein-containing Complex Intracellular Membrane-bounded Organelle	Endosome Cytosol
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding	Protein Binding Phosphatidylinositol Binding
	Biological Process	Intracellular Protein Transport Receptor Internalization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Lamellipodium Morphogenesis	Protein Transport Regulation Of Macroautophagy Retrograde Transport, Endosome To Golgi
Pathways
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Allergic sensitization ( 30013184) Birth weight ( 31043758) Breast cancer ( 23535729) Inflammatory bowel disease ( 23128233) Neutrophil count ( 32888494) Platelet count ( 32888494) Rosacea symptom severity ( 29771307) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 32888494)
Interacting Genes		48 interacting genes: ACVR1B ACVR2B AGTRAP APP ARFIP2 ARL6IP1 ARMC12 ATXN7 CCDC148 CHRNG CMTM4 CMTM5 COQ3 EGFR F2R FAM25A FAM25C FAM25G FKBP7 FUNDC1 HCCS HGS INSR LEPR LIME1 MPC2 PDGFRB PLIN3 RABAC1 REEP5 REEP6 RHEX RTN3 RTN4 SASH1 SDCBP SDR16C5 SFT2D1 SH3GLB1 SNX2 SNX32 SNX6 SYNGR1 SYP TK1 TMEM239 UFD1 VPS35	11 interacting genes: C22orf39 EML2 GRXCR1 MNS1 NME7 SNX1 SNX2 SPANXB1 TEX11 TFIP11 TSG101
Entrez ID		6642	254122
HPRD ID		03171	08090
Ensembl ID		ENSG00000028528	ENSG00000172803
Uniprot IDs		Q13596	Q86XE0
PDB IDs		2I4K 4FZS	6E8R
Enriched GO Terms of Interacting Partners?
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