SLC2A1 and PDIA3

Number of citations of the paper that reports this interaction (PubMedID 9153243)
19

Data Source:
BioGRID (pull down)
HPRD (in vivo)

		SLC2A1	PDIA3
Description		solute carrier family 2 member 1	protein disulfide isomerase family A member 3
Image
GO Annotations	Cellular Component	Golgi Membrane Photoreceptor Inner Segment Female Pronucleus Cytosol Plasma Membrane Integral Component Of Plasma Membrane Caveola Intercalated Disc Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Z Disc Midbody Cortical Actin Cytoskeleton Sarcolemma Melanosome Extracellular Exosome Blood Microparticle Presynapse	Extracellular Space Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Focal Adhesion Cell Surface Melanosome MHC Class I Peptide Loading Complex Phagocytic Vesicle Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Long-chain Fatty Acid Transporter Activity Glucose Transmembrane Transporter Activity Protein Binding Kinase Binding Dehydroascorbic Acid Transmembrane Transporter Activity Identical Protein Binding Xenobiotic Transmembrane Transporter Activity Protein Self-association D-glucose Transmembrane Transporter Activity	RNA Binding Protein Disulfide Isomerase Activity Cysteine-type Endopeptidase Activity Phospholipase C Activity Protein Binding Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity Identical Protein Binding
	Biological Process	Response To Hypoxia Central Nervous System Development Female Pregnancy Long-chain Fatty Acid Import Across Plasma Membrane L-ascorbic Acid Metabolic Process Cerebral Cortex Development Response To Insulin Cellular Response To Glucose Starvation Xenobiotic Transport Photoreceptor Cell Maintenance Protein-containing Complex Assembly Dehydroascorbic Acid Transport Cellular Response To Mechanical Stimulus Cellular Hyperosmotic Response Glucose Import Across Plasma Membrane Transport Across Blood-brain Barrier Response To Thyroglobulin Triiodothyronine Glucose Transmembrane Transport	Protein Folding Proteolysis Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cellular Response To Interleukin-7 Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Cellular hexose transport Vitamin C (ascorbate) metabolism Regulation of insulin secretion Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) Lactose synthesis	ER-Phagosome pathway ER-Phagosome pathway Calnexin/calreticulin cycle Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs		Resveratrol Carboxymethylcellulose	Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Birth weight ( 31043758) Cardiac hypertrophy ( 21348951) Immature fraction of reticulocytes ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494 27863252) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Pre-treatment viral load in HIV-1 infection ( 31219150) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) White blood cell count ( 32888494)	Blood protein levels ( 30072576) Lead levels ( 26025379) Liver volume ( 34128465) Triglyceride levels ( 32203549)
Interacting Genes		24 interacting genes: ADNP BMP8B CALR CANX CCR2 CDKN1C CHRNB4 COPS6 FAAH GAPDH GCN1 GIPC1 GPR35 HSPB2 LTB4R2 PDIA3 PTK2B PTPRU SMAP2 STOM SUMO1 UBE2I VHL ZRSR2	25 interacting genes: APP BACE1 CACNB2 CALR CANX ERO1A ERP27 ESR1 FBLN5 GYPC HLA-A IFNG LINC01554 MDM2 MTNR1B OGT PCAT1 PLCB2 SEC11A SLC12A3 SLC2A1 STAT3 SUMO4 TAP1 UBE3A
Entrez ID		6513	2923
HPRD ID		00683	03625
Ensembl ID		ENSG00000117394	ENSG00000167004
Uniprot IDs		P11166 Q59GX2	P30101 V9HVY3
PDB IDs		1SUK 4PYP 5EQG 5EQH 5EQI 6THA	2ALB 2DMM 2H8L 3F8U 6ENY
Enriched GO Terms of Interacting Partners?
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