SLC2A1 and GCN1

		SLC2A1	GCN1
Description		solute carrier family 2 member 1	GCN1 activator of EIF2AK4
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Photoreceptor Inner Segment Female Pronucleus Cytosol Plasma Membrane Integral Component Of Plasma Membrane Caveola Intercalated Disc Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Z Disc Midbody Cortical Actin Cytoskeleton Sarcolemma Melanosome Extracellular Exosome Blood Microparticle Presynapse	Cytoplasm Cytosol Ribosome Polysome Membrane
	Molecular Function	Long-chain Fatty Acid Transporter Activity Glucose Transmembrane Transporter Activity Protein Binding Kinase Binding Dehydroascorbic Acid Transmembrane Transporter Activity Identical Protein Binding Xenobiotic Transmembrane Transporter Activity Protein Self-association D-glucose Transmembrane Transporter Activity	RNA Binding Translation Factor Activity, RNA Binding Protein Kinase Regulator Activity Protein Kinase Binding Ribosome Binding Cadherin Binding
	Biological Process	Response To Hypoxia Central Nervous System Development Female Pregnancy Long-chain Fatty Acid Import Across Plasma Membrane L-ascorbic Acid Metabolic Process Cerebral Cortex Development Response To Insulin Cellular Response To Glucose Starvation Xenobiotic Transport Photoreceptor Cell Maintenance Protein-containing Complex Assembly Dehydroascorbic Acid Transport Cellular Response To Mechanical Stimulus Cellular Hyperosmotic Response Glucose Import Across Plasma Membrane Transport Across Blood-brain Barrier Response To Thyroglobulin Triiodothyronine Glucose Transmembrane Transport	Translation Regulation Of Translation Positive Regulation Of Kinase Activity Cellular Response To Amino Acid Starvation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cellular Response To Leucine Starvation
Pathways		Cellular hexose transport Vitamin C (ascorbate) metabolism Regulation of insulin secretion Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) Lactose synthesis	Response of EIF2AK4 (GCN2) to amino acid deficiency
Drugs		Resveratrol Carboxymethylcellulose
Diseases
GWAS		Birth weight ( 31043758) Cardiac hypertrophy ( 21348951) Immature fraction of reticulocytes ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494 27863252) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Pre-treatment viral load in HIV-1 infection ( 31219150) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) White blood cell count ( 32888494)
Interacting Genes		24 interacting genes: ADNP BMP8B CALR CANX CCR2 CDKN1C CHRNB4 COPS6 FAAH GAPDH GCN1 GIPC1 GPR35 HSPB2 LTB4R2 PDIA3 PTK2B PTPRU SMAP2 STOM SUMO1 UBE2I VHL ZRSR2	4 interacting genes: MYC SLC2A1 SUMO2 YWHAQ
Entrez ID		6513	10985
HPRD ID		00683	16127
Ensembl ID		ENSG00000117394	ENSG00000089154
Uniprot IDs		P11166 Q59GX2	Q92616
PDB IDs		1SUK 4PYP 5EQG 5EQH 5EQI 6THA
Enriched GO Terms of Interacting Partners?
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