ACD and STIP1

Number of citations of the paper that reports this interaction (PubMedID 21044950)
51

Data Source:
BioGRID (two hybrid)

		ACD	STIP1
Description		ACD shelterin complex subunit and telomerase recruitment factor	stress induced phosphoprotein 1
Image
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleoplasm Telomerase Holoenzyme Complex Nuclear Body Shelterin Complex	Nucleus Golgi Apparatus Cytosol Protein-containing Complex Chaperone Complex Dynein Axonemal Particle
	Molecular Function	Protein Binding Telomeric DNA Binding Protein-containing Complex Binding DNA Polymerase Binding	RNA Binding Protein Binding Protein C-terminus Binding Hsp70 Protein Binding Chaperone Binding Hsp90 Protein Binding
	Biological Process	Telomere Maintenance Skeletal System Development Urogenital System Development Intracellular Protein Transport Telomere Maintenance Via Telomerase Telomere Capping Embryonic Limb Morphogenesis Protection From Non-homologous End Joining At Telomere Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomerase Segmentation Positive Regulation Of Telomerase Activity Positive Regulation Of Single-stranded Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region Establishment Of Protein Localization To Telomere	Cellular Response To Interleukin-7
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine Meiotic synapsis Packaging Of Telomere Ends Telomere Extension By Telomerase Polymerase switching on the C-strand of the telomere Processive synthesis on the C-strand of the telomere Telomere C-strand (Lagging Strand) Synthesis Telomere C-strand synthesis initiation Removal of the Flap Intermediate from the C-strand DNA Damage/Telomere Stress Induced Senescence Inhibition of DNA recombination at telomere	HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand RND1 GTPase cycle
Drugs			Copper
Diseases
GWAS		Hemoglobin levels ( 32327693) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Attention deficit hyperactivity disorder ( 21784300) Body shape index ( 34021172) Crohn's disease ( 28067908) Fruit consumption ( 32066663) Monocyte count ( 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		65 interacting genes: ACTB ADPRH AFAP1L2 AIPL1 ANKMY2 ANXA8L1 APOBEC3F BAG3 CKB CTTN DBN1 DBNL DCX DPYSL3 EIF3G EIF4B ENO2 ENSA ESRP2 FAM131B FBXW7 FKBP6 GAPDH HSP90AB1 IPO5 IVL LASP1 LDHA LGALSL LLGL1 LRRC25 NCDN NTAQ1 NUDC NUDCD2 PAGE2 PDLIM2 PEX5 PFKP PGM2 POT1 RBKS RECQL4 RGS3 RPSA SBDS STIP1 STUB1 SULT1C2 TAGLN TBC1D10A TBCD TINF2 TOMM34 TRIM15 TRIM16 TRIM55 TRIM63 TUBB2A TUBB4B USP7 XRCC6 YWHAE ZFP36L1 ZNF790	25 interacting genes: ACD ACVR1 AIP APP CDC37 CLCN1 CLK1 EGFR ERBB2 FKBP4 FKBP5 HSP90AA1 HSPA14 HSPA1A HSPA1B HSPA8 LMO2 MAP3K8 OGT POT1 PRNP PTGES3 SUMO2 SUMO4 YIF1A
Entrez ID		65057	10963
HPRD ID		12417	05454
Ensembl ID		ENSG00000102977	ENSG00000168439
Uniprot IDs		A0A590TQL1 Q96AP0	P31948 V9HW72
PDB IDs		2I46 5H65 5I2X 5I2Y 5UN7 5XYF	1ELR 1ELW 2LNI 2NC9 3ESK 3FWV
Enriched GO Terms of Interacting Partners?
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