FNDC3B and BBS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FNDC3B	BBS2
Description		fibronectin type III domain containing 3B	Bardet-Biedl syndrome 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Cytosol Membrane Motile Cilium BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane
	Molecular Function	RNA Binding	Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process		Sperm Axoneme Assembly Visual Perception Protein Localization Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Melanosome Transport Protein Localization To Organelle Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Non-motile Cilium Assembly
Pathways			BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS		Bell's palsy ( 33602968) Central corneal thickness ( 32528159 31798171 29760442 30894546) Corneal hysteresis ( 30894546) Corneal resistance factor ( 31246245 30894546) Corneal structure ( 23291589) Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glaucoma (primary open-angle) ( 33627673) Glycated hemoglobin levels ( 34059833 28898252) Heart rate ( 23583979) Height ( 28552196 25282103 25429064 23563607 31562340 33713608) Hip circumference adjusted for BMI ( 28552196 34021172 25673412) Hypertrophic cardiomyopathy ( 33495596 33495597) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597) Immature fraction of reticulocytes ( 32888494 27863252) Intraocular pressure ( 29617998 25173106 31798171 29785010 30054594 28073927 29235454) Intraocular pressure (Goldman correlated) ( 30894546) Keratoconus ( 33649486) Mean corpuscular hemoglobin ( 32888494) Myocardial infarction ( 33532862) Parkinson's disease ( 26227905) PR interval ( 32439900) Pulse pressure ( 30224653) Red cell distribution width ( 32888494 27863252 28957414) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Triptolide cytotoxicity ( 26121980) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for BMI in smokers ( 28443625) Waist circumference adjusted for body mass index ( 34021172 25673412 28448500) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		52 interacting genes: ABHD11 ABHD8 ADGRF5 BBS2 BICRAL BRWD1 C10orf55 C10orf82 C19orf54 C22orf15 CAMK2D CAPN3 CEMP1 DAPL1 DUSP10 ERCC6 GAS2L3 HAPLN2 KLHDC7B KRTAP11-1 L3MBTL3 MBD3L1 MCCD1 MVP NDUFAB1 PIK3R4 POGZ POU6F2 PRKAA2 REL RUSC1 SPSB2 SRARP STPG4 SUOX TEKT5 TEPSIN TESMIN TEX43 TEX48 TIAM1 TOX4 TRAF2 TRIM35 TRIM42 TRIP13 TTN UBAP2 USP54 VAC14 YPEL3 ZMYND19	25 interacting genes: APOC2 BHMT CES1 CETP CNOT1 EEF1A1 EPAS1 EXOC7 FHOD1 FNDC3B GOT2 HNRNPF HSCB HSF4 KCNK17 KRT18 LMO4 MAP2K5 MDFI NRF1 PAX2 PSME3 RBPMS SPTSSA WRNIP1
Entrez ID		64778	583
HPRD ID		10943	05855
Ensembl ID		ENSG00000075420	ENSG00000125124
Uniprot IDs		Q53EP0	Q9BXC9
PDB IDs
Enriched GO Terms of Interacting Partners?
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