BBS2 and HSCB

Number of citations of the paper that reports this interaction (PubMedID 18000879)
7

Data Source:
BioGRID (two hybrid)

		BBS2	HSCB
Description		Bardet-Biedl syndrome 2	HscB mitochondrial iron-sulfur cluster cochaperone
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane Motile Cilium BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane	Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	ATPase Activator Activity Molecular_function Protein Binding Identical Protein Binding Metal Ion Binding Chaperone Binding
	Biological Process	Sperm Axoneme Assembly Visual Perception Protein Localization Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Melanosome Transport Protein Localization To Organelle Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Non-motile Cilium Assembly	Iron-sulfur Cluster Assembly [2Fe-2S] Cluster Assembly Regulation Of Catalytic Activity Protein Complex Oligomerization Protein Maturation By Iron-sulfur Cluster Transfer
Pathways		BBSome-mediated cargo-targeting to cilium	Mitochondrial protein import Mitochondrial protein import Mitochondrial iron-sulfur cluster biogenesis
Drugs
Diseases
GWAS			Breast size ( 27182965) Diastolic blood pressure ( 27841878) Esophageal cancer and gastric cancer ( 20729852) Mean platelet volume ( 32888494) Myeloproliferative neoplasms ( 33057200) Pancreatic cancer ( 25086665) Red cell distribution width ( 27863252) Systolic blood pressure ( 27841878) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		25 interacting genes: APOC2 BHMT CES1 CETP CNOT1 EEF1A1 EPAS1 EXOC7 FHOD1 FNDC3B GOT2 HNRNPF HSCB HSF4 KCNK17 KRT18 LMO4 MAP2K5 MDFI NRF1 PAX2 PSME3 RBPMS SPTSSA WRNIP1	5 interacting genes: AGTRAP BBS1 BBS2 BBS4 FBN1
Entrez ID		583	150274
HPRD ID		05855	16289
Ensembl ID		ENSG00000125124	ENSG00000100209
Uniprot IDs		Q9BXC9	A0A384NYJ4 B0QYH2 Q8IWL3
PDB IDs			3BVO
Enriched GO Terms of Interacting Partners?
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