BBS2 and BHMT

Number of citations of the paper that reports this interaction (PubMedID 18000879)
7

Data Source:
BioGRID (two hybrid)

		BBS2	BHMT
Description		Bardet-Biedl syndrome 2	betaine--homocysteine S-methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane Motile Cilium BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane	Cytosol Extracellular Exosome
	Molecular Function	Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Zinc Ion Binding Betaine-homocysteine S-methyltransferase Activity
	Biological Process	Sperm Axoneme Assembly Visual Perception Protein Localization Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Melanosome Transport Protein Localization To Organelle Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Non-motile Cilium Assembly	Protein Methylation Amino-acid Betaine Metabolic Process Amino-acid Betaine Catabolic Process S-adenosylmethionine Metabolic Process Regulation Of Homocysteine Metabolic Process L-methionine Salvage
Pathways		BBSome-mediated cargo-targeting to cilium	Sulfur amino acid metabolism Choline catabolism
Drugs			Methionine S-(D-Carboxybutyl)-L-Homocysteine
Diseases
GWAS			Betaine levels in individuals undergoing cardiac evaluation ( 26822151) Blood and toenail selenium levels ( 25343990) Blood metabolite levels ( 24816252) Blood trace element (Se levels) ( 23720494) Metabolite levels ( 23823483 23378610) Serum metabolite levels ( 33031748) Toenail selenium levels ( 25343990)
Interacting Genes		25 interacting genes: APOC2 BHMT CES1 CETP CNOT1 EEF1A1 EPAS1 EXOC7 FHOD1 FNDC3B GOT2 HNRNPF HSCB HSF4 KCNK17 KRT18 LMO4 MAP2K5 MDFI NRF1 PAX2 PSME3 RBPMS SPTSSA WRNIP1	6 interacting genes: ALG9 BBS1 BBS2 BBS4 LAMTOR3 LAMTOR5
Entrez ID		583	635
HPRD ID		05855	04200
Ensembl ID		ENSG00000125124	ENSG00000145692
Uniprot IDs		Q9BXC9	Q93088 V9HWA4
PDB IDs			1LT7 1LT8 4M3P
Enriched GO Terms of Interacting Partners?
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