VPS16 and VPS18

Number of citations of the paper that reports this interaction (PubMedID 11382755)
35

Data Source:
HPRD (in vivo)

		VPS16	VPS18
Description		VPS16 core subunit of CORVET and HOPS complexes	VPS18 core subunit of CORVET and HOPS complexes
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Actin Filament AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane CORVET Complex Presynapse Glutamatergic Synapse
	Molecular Function	Actin Binding Protein Binding Actin Filament Binding	Actin Binding Protein Binding Syntaxin Binding Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Intracellular Protein Transport Endosome To Lysosome Transport Endosomal Transport Vacuole Fusion, Non-autophagic Autophagosome Maturation	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Lysosome Organization Endosome To Lysosome Transport Protein Ubiquitination Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Viral Entry Into Host Cell Organelle Fusion Regulation Of Synaptic Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS		Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483)	Hemoglobin ( 32888494) Malaria ( 31844061) Refractive error ( 32231278) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		17 interacting genes: AKTIP EXOC8 FBXO7 GNG13 HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP STX1A STX7 UVRAG VPS11 VPS18 VPS33A ZNF417	22 interacting genes: AKTIP CLCN3 COPB1 EP300 GGA1 GGA2 GGA3 HOOK1 MON1B RAB7A RILP SHANK3 STX1A STX6 STX7 STX8 UBE2D2 UVRAG VPS11 VPS16 VPS33A VPS45
Entrez ID		64601	57617
HPRD ID		12259	09776
Ensembl ID		ENSG00000215305	ENSG00000104142
Uniprot IDs		Q9H269	A0A024R9R3 Q9P253
PDB IDs		4BX9
Enriched GO Terms of Interacting Partners?
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