VPS16 and HOOK3

Number of citations of the paper that reports this interaction (PubMedID 18799622)
51

Data Source:
HPRD (in vivo)

		VPS16	HOOK3
Description		VPS16 core subunit of CORVET and HOPS complexes	hook microtubule tethering protein 3
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GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome	Pericentriolar Material Cytoplasm Cis-Golgi Network Centrosome Cytosol Microtubule Centriolar Satellite FHF Complex
	Molecular Function	Actin Binding Protein Binding Actin Filament Binding	Protein Binding Microtubule Binding Dynactin Binding Identical Protein Binding Dynein Light Chain Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Intracellular Protein Transport Endosome To Lysosome Transport Endosomal Transport Vacuole Fusion, Non-autophagic Autophagosome Maturation	Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Interkinetic Nuclear Migration Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Microtubule Anchoring At Centrosome Early Endosome To Late Endosome Transport Negative Regulation Of Neurogenesis Golgi Localization Protein Localization To Centrosome Neuronal Stem Cell Population Maintenance Protein Localization To Perinuclear Region Of Cytoplasm
Pathways
Drugs
Diseases
GWAS		Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483)	Zinc levels ( 26025379)
Interacting Genes		17 interacting genes: AKTIP EXOC8 FBXO7 GNG13 HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP STX1A STX7 UVRAG VPS11 VPS18 VPS33A ZNF417	13 interacting genes: AKTIP CTIF HOOK1 HOOK2 IDO2 KRT13 KRT27 MAPT MEOX2 MORC3 PNMA5 VPS16 VPS41
Entrez ID		64601	84376
HPRD ID		12259	09699
Ensembl ID		ENSG00000215305	ENSG00000168172
Uniprot IDs		Q9H269	Q86VS8
PDB IDs		4BX9	5J8E 6B9H
Enriched GO Terms of Interacting Partners?
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