PLA2G2F and NBL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLA2G2F	NBL1
Description		phospholipase A2 group IIF	NBL1, DAN family BMP antagonist
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane	Extracellular Space
	Molecular Function	Phospholipase A2 Activity Calcium Ion Binding Phospholipid Binding Calcium-dependent Phospholipase A2 Activity	Protein Binding Morphogen Activity BMP Binding Identical Protein Binding Receptor Ligand Activity
	Biological Process	Phospholipid Metabolic Process Lipid Catabolic Process Arachidonic Acid Metabolic Process Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Negative Regulation Of T Cell Proliferation Innate Immune Response Arachidonic Acid Secretion	Signal Transduction Nervous System Development Animal Organ Morphogenesis Negative Regulation Of BMP Signaling Pathway Sequestering Of BMP In Extracellular Matrix Sequestering Of BMP From Receptor Via BMP Binding Positive Regulation Of Neuron Differentiation Determination Of Dorsal Identity Neuron Projection Morphogenesis Negative Regulation Of Monocyte Chemotaxis
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA
Drugs
Diseases
GWAS		Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471)	Blood protein levels ( 30072576) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Bronchopulmonary dysplasia in preterm infants ( 30113228) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Lymphocyte counts ( 32888494) Serum thyroid-stimulating hormone levels ( 24852370) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		3 interacting genes: MICOS10-NBL1 NBL1 VENTX	14 interacting genes: BAG6 DPEP2NB HPCAL1 KRTAP11-1 LRIG1 MEOX2 MRPL12 NCALD NCS1 PLA2G2F SLPI UBQLN1 UBQLN2 ZMIZ2
Entrez ID		64600	4681
HPRD ID		07499	09001
Ensembl ID		ENSG00000158786	ENSG00000158747
Uniprot IDs		Q9BZM2	A0A087WTY6 P41271
PDB IDs			4X1J 4YU8
Enriched GO Terms of Interacting Partners?
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