NBL1 and PLA2G2F

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NBL1	PLA2G2F
Description		NBL1, DAN family BMP antagonist	phospholipase A2 group IIF
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Extracellular Region Cytosol Plasma Membrane
	Molecular Function	Protein Binding Morphogen Activity BMP Binding Identical Protein Binding Receptor Ligand Activity	Phospholipase A2 Activity Calcium Ion Binding Phospholipid Binding Calcium-dependent Phospholipase A2 Activity
	Biological Process	Signal Transduction Nervous System Development Animal Organ Morphogenesis Negative Regulation Of BMP Signaling Pathway Sequestering Of BMP In Extracellular Matrix Sequestering Of BMP From Receptor Via BMP Binding Positive Regulation Of Neuron Differentiation Determination Of Dorsal Identity Neuron Projection Morphogenesis Negative Regulation Of Monocyte Chemotaxis	Phospholipid Metabolic Process Lipid Catabolic Process Arachidonic Acid Metabolic Process Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Negative Regulation Of T Cell Proliferation Innate Immune Response Arachidonic Acid Secretion
Pathways			Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Bronchopulmonary dysplasia in preterm infants ( 30113228) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Lymphocyte counts ( 32888494) Serum thyroid-stimulating hormone levels ( 24852370) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471)
Interacting Genes		14 interacting genes: BAG6 DPEP2NB HPCAL1 KRTAP11-1 LRIG1 MEOX2 MRPL12 NCALD NCS1 PLA2G2F SLPI UBQLN1 UBQLN2 ZMIZ2	3 interacting genes: MICOS10-NBL1 NBL1 VENTX
Entrez ID		4681	64600
HPRD ID		09001	07499
Ensembl ID		ENSG00000158747	ENSG00000158786
Uniprot IDs		A0A087WTY6 P41271	Q9BZM2
PDB IDs		4X1J 4YU8
Enriched GO Terms of Interacting Partners?
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